Genetic polymorphisms associated with susceptibility to COVID-19 disease and severity: A systematic review and meta-analysis

C Dieter, LA Brondani, CB Leitão, F Gerchman… - PLoS …, 2022 - journals.plos.org
Although advanced age and presence of comorbidities significantly impact the variation
observed in the clinical symptoms of COVID-19, it has been suggested that genetic variants …

Human genetic basis of coronavirus disease 2019

H Deng, X Yan, L Yuan - Signal transduction and targeted therapy, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) caused by a novel coronavirus, severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in considerable …

Host genetic polymorphisms involved in long-term symptoms of COVID-19

W Udomsinprasert, N Nontawong… - Emerging Microbes & …, 2023 - Taylor & Francis
Host genetic polymorphisms are recognized as a critical determinant of diversity in clinical
symptoms of Coronavirus disease 2019 (COVID-19). Accordingly, this study aimed to …

Role of genetic variants and host polymorphisms on COVID‐19: From viral entrance mechanisms to immunological reactions

A Adli, M Rahimi, R Khodaie… - Journal of Medical …, 2022 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), caused by a highly pathogenic emerging
virus, is called severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Knowledge …

COVID‐19: An Overview of SARS‐CoV‐2 Variants—The Current Vaccines and Drug Development

N Bostanghadiri, P Ziaeefar, MG Mofrad… - BioMed Research …, 2023 - Wiley Online Library
The world is presently in crisis facing an outbreak of a health‐threatening microorganism
known as COVID‐19, responsible for causing uncommon viral pneumonia in humans. The …

Potential protective effect against SARS-CoV-2 infection by APOE rs7412 polymorphism

I Espinosa-Salinas, G Colmenarejo… - Scientific Reports, 2022 - nature.com
The pandemic burden caused by the SARS-CoV-2 coronavirus constitutes a global public
health emergency. Increasing understanding about predisposing factors to infection and …

An interplay between oxidative stress (Lactate dehydrogenase) and inflammation (Anisocytosis) mediates COVID-19 severity defined by routine clinical markers

M Alonso-Bernáldez, A Cuevas-Sierra, V Micó… - Antioxidants, 2023 - mdpi.com
Viral infections activate the innate immune response and the secretion of inflammatory
cytokines. They also alter oxidative stress markers, which potentially can have an …

Proinflammatory and hepatic features related to morbidity and fatal outcomes in COVID-19 patients

O Ramos-Lopez, R San-Cristobal… - Journal of Clinical …, 2021 - mdpi.com
Objective: to screen putative associations between liver markers and proinflammatory-
related features concerning infectious morbidity and fatal outcomes in COVID-19 patients …

Computational network analysis of host genetic risk variants of severe COVID-19

SB Alsaedi, K Mineta, X Gao, T Gojobori - Human Genomics, 2023 - Springer
Background Genome-wide association studies have identified numerous human host
genetic risk variants that play a substantial role in the host immune response to SARS-CoV …

COVID-19 pandemic impact on trajectories in cardiometabolic health, physical activity, and functioning among adults from the 2006–2020 health and retirement study

HA Beydoun, MA Beydoun, RS Gautam… - The Journals of …, 2022 - academic.oup.com
Background The aim of this study was to evaluate the impact of the COVID-19 pandemic on
trajectories in cardiometabolic health, physical activity, and functioning among US older …