Are physicochemical properties shaping the allergenic potency of animal allergens?

J Costa, C Villa, K Verhoeckx… - Clinical Reviews in …, 2022 - Springer
Key determinants for the development of an allergic response to an otherwise 'harmless'
food protein involve different factors like the predisposition of the individual, the timing, the …

Recent trends in protein and peptide-based biomaterials for advanced drug delivery

A Varanko, S Saha, A Chilkoti - Advanced drug delivery reviews, 2020 - Elsevier
Engineering protein and peptide-based materials for drug delivery applications has gained
momentum due to their biochemical and biophysical properties over synthetic materials …

Spectroscopy and molecular simulation on the interaction of Nano-Kaempferol prepared by oil-in-water with two carrier proteins: An investigation of protein–protein …

M Kaffash, S Tolou-Shikhzadeh-Yazdi… - … Acta Part A: Molecular …, 2024 - Elsevier
In this work, the interaction of human serum albumin (HSA) and human holo-transferrin
(HTF) with the prepared Nano-Kaempferol (Nano-KMP) through oil-in-water procedure was …

[HTML][HTML] Regulation of zinc-dependent enzymes by metal carrier proteins

MW Thompson - Biometals, 2022 - Springer
Zn2+ ions are essential in many physiological processes, including enzyme catalysis,
protein structural stabilization, and the regulation of many proteins. The affinities of proteins …

[HTML][HTML] Iron homeostasis in the liver

ER Anderson, YM Shah - Comprehensive Physiology, 2013 - ncbi.nlm.nih.gov
Iron is an essential nutrient that is tightly regulated. A principal function of the liver is the
regulation of iron homeostasis. The liver senses changes in systemic iron requirements and …

Lactoferrin, a bird's eye view

HJ Vogel - Biochemistry and Cell Biology, 2012 - cdnsciencepub.com
Lactoferrin is an abundant iron-binding protein in milk. This 80 kDa bilobal glycoprotein is
also present in several other secreted bodily fluids, as well as in the secondary granules of …

Iron-withholding strategy in innate immunity

ST Ong, JZS Ho, B Ho, JL Ding - Immunobiology, 2006 - Elsevier
The knowledge of how organisms fight infections has largely been built upon the ability of
host innate immune molecules to recognize microbial determinants. Although of …

[HTML][HTML] Human transferrin: An inorganic biochemistry perspective

AMN Silva, T Moniz, B de Castro, M Rangel - Coordination Chemistry …, 2021 - Elsevier
Transferrin (Tf) is an essential protein, probably ubiquitous to all metazoans. The main
function of this family of proteins is to bind and transport ferric ions, increasing Fe (III) …

[HTML][HTML] The crystal structure of iron-free human serum transferrin provides insight into inter-lobe communication and receptor binding

J Wally, PJ Halbrooks, C Vonrhein, MA Rould… - Journal of Biological …, 2006 - ASBMB
Serum transferrin reversibly binds iron in each of two lobes and delivers it to cells by a
receptor-mediated, pH-dependent process. The binding and release of iron result in a large …

Carbonate-sensitive phytotransferrin controls high-affinity iron uptake in diatoms

JB McQuaid, AB Kustka, M Oborník, A Horák… - Nature, 2018 - nature.com
In vast areas of the ocean, the scarcity of iron controls the growth and productivity of
phytoplankton,. Although most dissolved iron in the marine environment is complexed with …