Application prospect of circular RNA-based neoantigen vaccine in tumor immunotherapy

M Li, Y Wang, P Wu, S Zhang, Z Gong, Q Liao, C Guo… - Cancer letters, 2023 - Elsevier
Neoantigen is a protein produced by mutant gene, which is only expressed in tumor cells. It
is an ideal target for therapeutic tumor vaccines. Although synthetic long peptide (SLP) …

LncRNAs‐circRNAs as Rising Epigenetic Binary Superstars in Regulating Lipid Metabolic Reprogramming of Cancers

S Liu, B Jiao, H Zhao, X Liang, F Jin, X Liu… - Advanced …, 2024 - Wiley Online Library
As one of novel hallmarks of cancer, lipid metabolic reprogramming has recently been
becoming fascinating and widely studied. Lipid metabolic reprogramming in cancer is …

Circular RNA cFAM210A, degradable by HBx, inhibits HCC tumorigenesis by suppressing YBX1 transactivation

J Yu, W Li, G Hou, D Sun, Y Yang, S Yuan… - … & Molecular Medicine, 2023 - nature.com
Hepatitis B protein x (HBx) has been reported to promote tumorigenesis in hepatitis B virus
(HBV)-related hepatocellular carcinoma (HCC), but the mechanism awaits further …

circRNF13, a novel N6-methyladenosine-modified circular RNA, enhances radioresistance in cervical cancer by increasing CXCL1 mRNA stability

J Shi, X Rui, C Han, C Wang, L Xu, X Jiang - Cell Death Discovery, 2023 - nature.com
Abstract Background Circular RNAs (circRNAs) and N6-methyladenosine (m6A) have been
shown to play an increasingly critical role in the development of different cancers. However …

Novel insights into the multifaceted roles of m6A-modified LncRNAs in cancers: biological functions and therapeutic applications

J Tang, J Zhang, Y Lu, J He, H Wang, B Liu, C Tu… - Biomarker research, 2023 - Springer
Abstract N6-methyladenosine (m6A) is considered as the most common and important
internal transcript modification in several diseases like type 2 diabetes, schizophrenia and …

Comprehensive Analysis of the Transcriptome-Wide m6A Methylome in Shaziling Pig Testicular Development

C Chen, X Tang, S Yan, A Yang, J Xiang… - International Journal of …, 2023 - mdpi.com
RNA N 6-methyladenosine (m6A) modification is one of the principal post-transcriptional
modifications and plays a dynamic role in testicular development and spermatogenesis …

New insights into the interaction between m6A modification and lncRNA in cancer drug resistance

Y Jin, Z Fan - Cell Proliferation, 2024 - Wiley Online Library
Drug resistance is perhaps the greatest obstacle in improving outcomes for cancer patients,
leading to recurrence, progression and metastasis of various cancers. Exploring the …

[HTML][HTML] N6-methyladenosine (m6A) in cancer therapeutic resistance: potential mechanisms and clinical implications

D Wang, Y Zhang, Q Li, A Zhang, J Xu, Y Li, W Li… - Biomedicine & …, 2023 - Elsevier
Cancer therapy resistance (CTR) is the development of cancer resistance to multiple
therapeutic strategies, which severely affects clinical response and leads to cancer …

RNA N6-methyladenosine (m6A) modification in HNSCC: molecular mechanism and therapeutic potential

X Sun, S Fu, X Yuan, X Pu, RK Wang, X Wang… - Cancer Gene …, 2023 - nature.com
Head and neck squamous cell carcinoma ranks seventh in incidence of malignant tumours
in the world. Although there are treatments including surgery, radiotherapy and …

Role of epigenetics in mycotoxin toxicity: A review

L Li, Z He, Y Shi, H Sun, B Yuan, J Cai, J Chen… - Environmental …, 2023 - Elsevier
Mycotoxins can induce cell cycle disorders, cell proliferation, oxidative stress, and apoptosis
through pathways such as those associated with MAPK, JAK2/STAT3, and Bcl-w/caspase-3 …