A review and database of snake venom proteomes

T Tasoulis, GK Isbister - Toxins, 2017 - mdpi.com
Advances in the last decade combining transcriptomics with established proteomics
methods have made possible rapid identification and quantification of protein families in …

[HTML][HTML] Strategies in 'snake venomics' aiming at an integrative view of compositional, functional, and immunological characteristics of venoms

B Lomonte, JJ Calvete - Journal of Venomous Animals and Toxins …, 2017 - SciELO Brasil
This work offers a general overview on the evolving strategies for the proteomic analysis of
snake venoms, and discusses how these may be combined through diverse experimental …

Convergent evolution of pain-inducing defensive venom components in spitting cobras

TD Kazandjian, D Petras, SD Robinson, J van Thiel… - Science, 2021 - science.org
Convergent evolution provides insights into the selective drivers underlying evolutionary
change. Snake venoms, with a direct genetic basis and clearly defined functional …

Old World Vipers—a review about snake venom proteomics of Viperinae and their variations

M Damm, BF Hempel, RD Süssmuth - Toxins, 2021 - mdpi.com
Fine-tuned by millions of years of evolution, snake venoms have frightened but also
fascinated humanity and nowadays they constitute potential resources for drug …

Proteomic analysis to unravel the complex venom proteome of eastern India Naja naja: Correlation of venom composition with its biochemical and pharmacological …

S Dutta, A Chanda, B Kalita, T Islam, A Patra… - Journal of …, 2017 - Elsevier
The complex venom proteome of the eastern India (EI) spectacled cobra (Naja naja) was
analyzed using tandem mass spectrometry of cation-exchange venom fractions. About 75 …

Adaptive evolution of distinct prey-specific toxin genes in rear-fanged snake venom

CM Modahl, Mrinalini, S Frietze… - Proceedings of the …, 2018 - royalsocietypublishing.org
Venom proteins evolve rapidly, and as a trophic adaptation are excellent models for
predator–prey evolutionary studies. The key to a deeper understanding of venom evolution …

How the cobra got its flesh-eating venom: Cytotoxicity as a defensive innovation and its co-evolution with hooding, aposematic marking, and spitting

N Panagides, TNW Jackson, MP Ikonomopoulou… - Toxins, 2017 - mdpi.com
The cytotoxicity of the venom of 25 species of Old World elapid snake was tested and
compared with the morphological and behavioural adaptations of hooding and spitting. We …

Venomics of Naja sputatrix, the Javan spitting cobra: A short neurotoxin-driven venom needing improved antivenom neutralization

NH Tan, KY Wong, CH Tan - Journal of proteomics, 2017 - Elsevier
The venom proteome of Naja sputatrix (Javan spitting cobra) was elucidated through
reverse-phase HPLC, nano-ESI-LCMS/MS and data mining. A total of 97 distinct protein …

Cytotoxicity of Snake Venoms and Cytotoxins From Two Southeast Asian Cobras (Naja sumatrana, Naja kaouthia): Exploration of Anticancer Potential, Selectivity …

HP Chong, KY Tan, CH Tan - Frontiers in Molecular Biosciences, 2020 - frontiersin.org
Venoms of cobras (Naja spp.) contain high abundances of cytotoxins, which contribute to
tissue necrosis in cobra envenomation. The tissue-necrotizing activity of cobra cytotoxins …

Venomics of Bungarus caeruleus (Indian krait): Comparable venom profiles, variable immunoreactivities among specimens from Sri Lanka, India and Pakistan

AMF Oh, CH Tan, GC Ariaranee, N Quraishi… - Journal of proteomics, 2017 - Elsevier
Abstract The Indian krait (Bungarus caeruleus) is one of the “Big Four” venomous snakes
widely distributed in South Asia. The present venomic study reveals that its venom (Sri …