Phenomics, the complexity of microglia phenotypes and their related functions compels the
continuous study of microglia in disease animal models to find druggable targets for …

Cannabidiol (CBD) is the main non-psychotropic cannabinoid derived from cannabis
(Cannabis sativa L., fam. Cannabaceae). CBD has received approval by the Food and Drug …

In the central nervous system, some specific phosphodiesterase (PDE) isoforms modulate
pathways involved in neuronal plasticity. Accumulating evidence suggests that PDE9 may …

To study the anti‐inflammatory potential of the two synthetic cannabinoids 4′‐F‐CBD and
HU‐910, we used post‐natal brain cultures of mouse microglial cells and astrocytes …

Cannabinoids are lipophilic substances derived from Cannabis sativa that can exert a
variety of effects in the human body. They have been studied in cellular and animal models …

Cannabis sativa products have historically been used for healing purposes; now their
biological properties are supported with scientific evidence, but modern research has not yet …

Cannabis contains over 500 different compounds, including cannabinoids, terpenoids, and
flavonoids. Cannabidiol (CBD) is a non-psychoactive constituent, whereas beta …

Background: Status epilepticus (SE) is a series of seizures that can lead to serious
neurological damages. Cannabidiol (CBD) is extracted from the cannabis plant, which has …

Neuroinflammation stands as a critical player in the pathogenesis of diverse neurological
disorders, with microglial cells playing a central role in orchestrating the inflammatory …

Neuroinflammation is initiated in response to a variety of endogenous and exogenous
sources. As the resident macrophages of the central nervous system, the polarization of …