[HTML][HTML] Childhood and adolescent obesity: a review

AR Kansra, S Lakkunarajah, MS Jay - Frontiers in pediatrics, 2021 - frontiersin.org
Obesity is a complex condition that interweaves biological, developmental, environmental,
behavioral, and genetic factors; it is a significant public health problem. The most common …

[HTML][HTML] Hepatokines and adipokines in NASH-related hepatocellular carcinoma

O Kucukoglu, JP Sowa, GD Mazzolini, WK Syn… - Journal of …, 2021 - Elsevier
The incidence of hepatocellular carcinoma (HCC) is increasing in industrialized societies;
this is likely secondary to the increasing burden of non-alcoholic fatty liver disease (NAFLD) …

[HTML][HTML] Prevention of obesity and metabolic syndrome in children

JW Gregory - Frontiers in endocrinology, 2019 - frontiersin.org
In recent decades, the prevalence of overweight and obesity has become increasingly
common such that it is now the major nutritional problem worldwide. Obesity occurs when …

[HTML][HTML] Insulin-resistance in paediatric age: Its magnitude and implications

M Al-Beltagi, AS Bediwy, NK Saeed - World journal of diabetes, 2022 - ncbi.nlm.nih.gov
Insulin resistance (IR) is insulin failure in normal plasma levels to adequately stimulate
glucose uptake by the peripheral tissues. IR is becoming more common in children and …

Genetic predisposition in type 2 diabetes: a promising approach toward a personalized management of diabetes

MM Sirdah, NS Reading - Clinical Genetics, 2020 - Wiley Online Library
Diabetes mellitus, also known simply as diabetes, has been described as a chronic and
complex endocrine metabolic disorder that is a leading cause of death across the globe. It is …

The increasing trend of Type 2 diabetes in youth: An overview

E Buttermore, V Campanella, R Priefer - Diabetes & Metabolic Syndrome …, 2021 - Elsevier
Abstract Introduction Pediatric Type 2 Diabetes Mellitus (T2DM) is increasing in incidence,
largely in correlation with global childhood obesity crisis. Complications Early detection and …

[HTML][HTML] Oxidative stress in type 2 diabetes: The case for future pediatric redoxomics studies

SN Alu, EA Los, GA Ford, WL Stone - Antioxidants, 2022 - mdpi.com
Considerable evidence supports the role of oxidative stress in adult type 2 diabetes (T2D).
Due to increasing rates of pediatric obesity, lack of physical activity, and consumption of …

[HTML][HTML] Role of somatostatin in the regulation of central and peripheral factors of satiety and obesity

U Kumar, S Singh - International journal of molecular sciences, 2020 - mdpi.com
Obesity is one of the major social and health problems globally and often associated with
various other pathological conditions. In addition to unregulated eating behaviour …

Obesity and insulin resistance in children

VM Tagi, F Chiarelli - Current Opinion in Pediatrics, 2020 - journals.lww.com
The aim of this review is to present an updated frame and new insights of the numerous
pathways involved in the development of insulin resistance in obese patients, focusing on …

The metabolic syndrome in pediatrics: do we have a reliable definition? A systematic review

A Tropeano, D Corica, A Li Pomi, G Pepe… - European Journal of …, 2021 - academic.oup.com
Objective Metabolic syndrome is a cluster of cardio-metabolic risk factors associated with an
increased risk of cardiovascular disease and type 2 diabetes. In the last two decades …