Liver cirrhosis is an increasing public health threat worldwide. Malnutrition is a serious
complication of cirrhosis and is associated with worse outcomes. With this review, we aim to …

Background Sarcopenia (loss of muscle mass) is common in cirrhosis and is associated with
poor outcomes. Current teaching recommends the use of protein supplementation and …

Sarcopenia is defined by muscle loss and muscle dysfunction. Sarcopenia is classified into
primary and secondary types, based on the cause. Primary sarcopenia is mainly aging …

Obesity and liver diseases are associated with the disruption of the circadian clock that
orchestrates mammalian physiology to optimize nutrient metabolism and storage. Here, we …

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
worldwide. Up to one third of individuals with NAFLD will develop nonalcoholic …

With aging and other muscle wasting diseases, men and women undergo similar
pathological changes in skeletal muscle: increased inflammation, enhanced oxidative …

Background & Aims Low testosterone and sarcopenia are common in men with cirrhosis and
both are associated with increased mortality. Whether testosterone therapy in cirrhosis …

A wealth of observational studies show that low testosterone is associated with insulin
resistance and with an increased risk of diabetes and the metabolic syndrome. Experimental …

The prevalence of osteoporosis and sarcopenia is significantly higher in patients with liver
disease than in those without liver disease and osteoporosis and sarcopenia negatively …

This narrative review presents an overview of current knowledge on fertility and reproductive
hormone changes in aging men, the factors driving and modulating these changes, their …