Overactive bladder syndrome with and without urinary incontinence and related conditions,
signs, and disorders such as detrusor overactivity, neurogenic lower urinary tract …

Underactive bladder (UAB), which has been described as a symptom complex suggestive of
detrusor underactivity, is usually characterized by prolonged urination time with or without a …

Pharmacological management of urinary incontinence (UI) is currently based on
antimuscarinic and beta-3-agonist drugs. Botulinum toxin A detrusor injections represent an …

Background Diabetic neuropathic pain is poorly controlled by analgesics, and the precise
molecular mechanisms underlying hyperalgesia remain unclear. The KCNQ2/3/5 channels …

Paclitaxel-induced peripheral neuropathy (PIPN) and associated neuropathic pain are the
most common and serious adverse effects experienced by cancer patients receiving …

We compared the effects of two anesthetics, isoflurane and urethane on bladder function in
rats. Arterial pressure, cystometry (CMG), and rhythmic bladder contractions (RBCs) under …

Transient receptor potential melastatin 8 (TRPM8) channels may contribute to the
pathophysiological bladder afferent hyperactivity, thus a TRPM8 antagonist would be a …

Key points KV7 channels are a family of voltage‐dependent K+ channels expressed in many
cell types, which open in response to membrane depolarization to regulate cell excitability …

Transient receptor potential ankyrin 1 (TRPA1) channel expressed by urothelial cells and
bladder sensory nerve fibers might act as a bladder mechanosensor and nociceptive …

Pelvic nerve (PN) bladder primary afferent neurons were retrogradely labeled by
intraparenchymal (IPar) microinjection of fluorescent tracer or intravesical (IVes) infusion of …