Inherited retinal diseases (IRDs) cause progressive loss of light-sensitive photoreceptors in the eye and can lead to blindness. Gene-based therapies for IRDs have shown remarkable …
G Xiao, Q He, L Liu, T Zhang, M Zhou, X Li… - Journal of translational …, 2022 - Springer
Background Although anxiety disorders are one of the most prevalent mental disorders, their underlying biological mechanisms have not yet been fully elucidated. In recent years …
Z Yun, Z Guo, X Li, Y Shen, M Nan, Q Dong… - Cancer …, 2023 - Wiley Online Library
Background Metabolic disorders are a hallmark feature of cancer. However, the evidence for the causality of circulating metabolites to promote or prevent colorectal cancer (CRC) is still …
Diabetic retinopathy (DR), the leading cause of blindness in working-age adults, is one of the most common complications of diabetes mellitus (DM) featured by metabolic disorders …
M Power, S Das, K Schütze, V Marigo, P Ekström… - Progress in Retinal and …, 2020 - Elsevier
The cellular mechanisms underlying hereditary photoreceptor degeneration are still poorly understood, a problem that is exacerbated by the enormous genetic heterogeneity of this …
A Annibal, RG Tharyan, MF Schonewolff, H Tam… - Nature …, 2021 - nature.com
The metabolome represents a complex network of biological events that reflects the physiologic state of the organism in health and disease. Additionally, specific metabolites …
IE Acar, L Lores-Motta, JM Colijn, MA Meester-Smoor… - Ophthalmology, 2020 - Elsevier
Purpose The current study aimed to identify metabolites associated with age-related macular degeneration (AMD) by performing the largest metabolome association analysis in …
Retinopathy, including age-related macular degeneration (AMD), diabetic retinopathy (DR), and retinopathy of prematurity (ROP), are the leading cause of blindness among seniors …
Y Wang, S Liu, H Wang, Y Zhao… - Microsystems & …, 2022 - nature.com
Neuron interface devices can be used to explore the relationships between neuron firing and synaptic transmission, as well as to diagnose and treat neurological disorders, such as …