High Enantioselective and Large-Scale Production of Ursodeoxycholic Acid by Combination of Pd-and Hydroxysteroid Dehydrogenase-Catalyzed Hydrogenation

C Zeng, X Liu, C Sun, X Xu, L Peng - Organic Process Research & …, 2024 - ACS Publications
Ursodeoxycholic acid (UDCA) was synthesized from commercially available phytosterol-
derived bisnoralcohol with an overall yield of 57% by a six-step process. The absolute …

High Enantioselective and Large-Scale Production of Ursodeoxycholic Acid by Combination of Pd-and Hydroxysteroid Dehydrogenase-Catalyzed Hydrogenation

C Zeng, X Liu, C Sun, X Xu, L Peng - Organic Process Research & …, 2024 - Elsevier
Ursodeoxycholic acid (UDCA) was synthesized from commercially available phytosterol-
derived bisnoralcohol with an overall yield of 57% by a six-step process. The absolute …