Saturation editing of genomic regions by multiplex homology-directed repair

GM Findlay, EA Boyle, RJ Hause, JC Klein, J Shendure - Nature, 2014 - nature.com
Saturation mutagenesis,—coupled to an appropriate biological assay—represents a
fundamental means of achieving a high-resolution understanding of regulatory and protein …

Saturation editing of genomic regions by multiplex homology-directed repair

GM Findlay, EA Boyle, RJ Hause, JC Klein, J Shendure - Nature, 2014 - go.gale.com
Saturation mutagenesis (1, 2)--coupled to an appropriate biological assay--represents a
fundamental means of achieving a high-resolution understanding of regulatory (3) and …

[HTML][HTML] Saturation Editing of Genomic Regions by Multiplex Homology-Directed Repair

GM Findlay, EA Boyle, RJ Hause, J Klein, J Shendure - Nature, 2014 - ncbi.nlm.nih.gov
Abstract Saturation mutagenesis 1, 2–coupled to an appropriate biological assay–
represents a fundamental means of achieving a high-resolution understanding of regulatory …

[PDF][PDF] Saturation editing of genomic regions by multiplex homology-directed repair

GM Findlay, EA Boyle, RJ Hause, JC Klein, J Shendure - NATURE, 2014 - rnajc.ucsf.edu
Saturation mutagenesis1, 2—coupled to an appropriate biological assay—represents a
fundamental means of achieving a high-resolution understanding of regulatory3 and protein …

Saturation editing of genomic regions by multiplex homology-directed repair.

GM Findlay, EA Boyle, RJ Hause, JC Klein, J Shendure - Nature, 2014 - europepmc.org
Abstract Saturation mutagenesis 1, 2–coupled to an appropriate biological assay–
represents a fundamental means of achieving a high-resolution understanding of regulatory …

Saturation editing of genomic regions by multiplex homology-directed repair

GM Findlay, EA Boyle, RJ Hause, JC Klein… - …, 2014 - pubmed.ncbi.nlm.nih.gov
Saturation mutagenesis--coupled to an appropriate biological assay--represents a
fundamental means of achieving a high-resolution understanding of regulatory and protein …

Saturation editing of genomic regions by multiplex homology-directed repair

GM Findlay, EA Boyle, RJ Hause, JC Klein, J Shendure - Nature, 2014 - ideas.repec.org
The authors perform saturation mutagenesis of genomic regions in their native endogenous
chromosomal context by using CRISPR/Cas9 RNA-guided cleavage and multiplex …

[PDF][PDF] Saturation Editing of Genomic Regions by Multiplex Homology-Directed Repair

GM Findlay, EA Boyle, RJ Hause, J Klein, J Shendure - Nature, 2014 - Citeseer
Abstract Saturation mutagenesis1, 2–coupled to an appropriate biological assay–represents
a fundamental means of achieving a high-resolution understanding of regulatory3 and …

[PDF][PDF] Saturation editing of genomic regions by multiplex homology-directed repair

GM Findlay, EA Boyle, RJ Hause, JC Klein… - NATURE, 2014 - ggdpathway.wustl.edu
Saturation mutagenesis1, 2—coupled to an appropriate biological assay—represents a
fundamental means of achieving a high-resolution understanding of regulatory3 and protein …

[PDF][PDF] Saturation editing of genomic regions by multiplex homology-directed repair

GM Findlay, EA Boyle, RJ Hause… - …, 2014 - shendure-web.gs.washington.edu
Saturation mutagenesis1, 2—coupled to an appropriate biological assay—represents a
fundamental means of achieving a high-resolution understanding of regulatory3 and protein …