Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function

G Eraslan, E Drokhlyansky, S Anand, E Fiskin… - Science, 2022 - science.org
Understanding gene function and regulation in homeostasis and disease requires
knowledge of the cellular and tissue contexts in which genes are expressed. Here, we …

Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function.

G Eraslan, E Drokhlyansky, S Anand, E Fiskin… - Science (New York …, 2022 - europepmc.org
Understanding gene function and regulation in homeostasis and disease requires
knowledge of the cellular and tissue contexts in which genes are expressed. Here, we …

[HTML][HTML] Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function

G Eraslan, E Drokhlyansky, S Anand… - Science (New York …, 2022 - ncbi.nlm.nih.gov
RESULTS: We established a framework for multi-tissue human cell atlases and generated
an atlas of 209,126 snRNA-seq profiles from eight tissue types across 16 individuals …

Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function

G Eraslan, E Drokhlyansky, S Anand, E Fiskin… - paper.sciencenet.cn
Understanding gene function and regulation in homeostasis and disease requires
knowledge of the cellular and tissue contexts in which genes are expressed. Here, we …

Single-nucleus cross-tissue molecular reference maps to decipher disease gene function

G Eraslan, E Drokhlyansky, S Anand, A Subramanian… - bioRxiv, 2021 - biorxiv.org
Understanding the function of genes and their regulation in tissue homeostasis and disease
requires knowing the cellular context in which genes are expressed in tissues across the …

Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function

G Eraslan, E Drokhlyansky, S Anand… - … (New York, NY), 2022 - pubmed.ncbi.nlm.nih.gov
Understanding gene function and regulation in homeostasis and disease requires
knowledge of the cellular and tissue contexts in which genes are expressed. Here, we …

Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function

G Eraslan, E Drokhlyansky, S Anand, E Fiskin… - 2022 - dspace.mit.edu
Understanding gene function and regulation in homeostasis and disease requires
knowledge of the cellular and tissue contexts in which genes are expressed. Here, we …

[HTML][HTML] Single-nucleus cross-tissue molecular reference maps to decipher disease gene function

G Eraslan, E Drokhlyansky, S Anand, A Subramanian… - bioRxiv, 2021 - biorxiv.org
Understanding the function of genes and their regulation in tissue homeostasis and disease
requires knowing the cellular context in which genes are expressed in tissues across the …

Single-nucleus cross-tissue molecular reference maps to decipher disease gene function

G Eraslan, E Drokhlyansky, S Anand, A Subramanian… - 2021 - europepmc.org
Understanding the function of genes and their regulation in tissue homeostasis and disease
requires knowing the cellular context in which genes are expressed in tissues across the …