[HTML][HTML] Splenic SUMO1 controls systemic inflammation in experimental sepsis

A Youssef, BK Mohammed, A Prasad… - Frontiers in …, 2023 - frontiersin.org
Introduction The recent discovery of TAK981 (Subasumstat), the first-in-class selective
inhibitor of SUMOylation, enables new immune treatments. TAK981 is already in clinical …

Splenic SUMO1 controls systemic inflammation in experimental sepsis.

A Youssef, BK Mohammed, A Prasad… - Frontiers in …, 2023 - europepmc.org
Methods We used TAK981 in two sepsis models; polymicrobial peritonitis (CLP) and LPS
endotoxemia. Splenectomy was done in both models to study the role of spleen. Western …

Splenic SUMO1 controls systemic inflammation in experimental sepsis

A Youssef, BK Mohammed, A Prasad… - Frontiers in …, 2023 - pubmed.ncbi.nlm.nih.gov
Introduction The recent discovery of TAK981 (Subasumstat), the first-in-class selective
inhibitor of SUMOylation, enables new immune treatments. TAK981 is already in clinical …

[PDF][PDF] Splenic SUMO1 controls systemic inflammation in experimental sepsis

A Youssef, BK Mohammed, A Prasad, A del Aguila… - 2023 - researchgate.net
Methods: We used TAK981 in two sepsis models; polymicrobial peritonitis (CLP) and LPS
endotoxemia. Splenectomy was done in both models to study the role of spleen. Western …

[HTML][HTML] Splenic SUMO1 controls systemic inflammation in experimental sepsis

A Youssef, BK Mohammed, A Prasad… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Methods We used TAK981 in two sepsis models; polymicrobial peritonitis (CLP) and LPS
endotoxemia. Splenectomy was done in both models to study the role of spleen. Western …

[PDF][PDF] Splenic SUMO1 controls systemic inflammation in experimental sepsis

A Youssef, BK Mohammed, A Prasad, A del Aguila… - 2023 - researchgate.net
Methods: We used TAK981 in two sepsis models; polymicrobial peritonitis (CLP) and LPS
endotoxemia. Splenectomy was done in both models to study the role of spleen. Western …