[HTML][HTML] T-cells produce acidic niches in lymph nodes to suppress their own effector functions

H Wu, V Estrella, M Beatty, D Abrahams… - Nature …, 2020 - nature.com
The acidic pH of tumors profoundly inhibits effector functions of activated CD8+ T-cells. We
hypothesize that this is a physiological process in immune regulation, and that it occurs …

T-cells produce acidic niches in lymph nodes to suppress their own effector functions.

H Wu, V Estrella, M Beatty, D Abrahams… - Nature …, 2020 - europepmc.org
The acidic pH of tumors profoundly inhibits effector functions of activated CD8+ T-cells. We
hypothesize that this is a physiological process in immune regulation, and that it occurs …

T-cells produce acidic niches in lymph nodes to suppress their own effector functions

H Wu, V Estrella, M Beatty… - Nature …, 2020 - pubmed.ncbi.nlm.nih.gov
The acidic pH of tumors profoundly inhibits effector functions of activated CD8+ T-cells. We
hypothesize that this is a physiological process in immune regulation, and that it occurs …

[PDF][PDF] T-cells produce acidic niches in lymph nodes to suppress their own effector functions

H Wu, V Estrella, M Beatty, D Abrahams, A El-Kenawi - scholar.archive.org
Results Paracortical zones are acidic niches inside the lymph node. The pHe of inguinal
LNs in C57BL/6 (B6) mice was probed using pH-Low Insertion Peptide (pHLIP) a short …

T-cells produce acidic niches in lymph nodes to suppress their own effector functions

H Wu, V Estrella, M Beatty, D Abrahams, A El-Kenawi… - 2020 - digitalcommons.uri.edu
The acidic pH of tumors profoundly inhibits effector functions of activated CD8+ T-cells. We
hypothesize that this is a physiological process in immune regulation, and that it occurs …

T-cells produce acidic niches in lymph nodes to suppress their own effector functions

H Wu, V Estrella, M Beatty, D Abrahams… - NATURE …, 2020 - iris.unito.it
The acidic pH of tumors profoundly inhibits effector functions of activated CD8+ T-cells. We
hypothesize that this is a physiological process in immune regulation, and that it occurs …

[HTML][HTML] T-cells produce acidic niches in lymph nodes to suppress their own effector functions

H Wu, V Estrella, M Beatty, D Abrahams… - Nature …, 2020 - ncbi.nlm.nih.gov
The acidic pH of tumors profoundly inhibits effector functions of activated CD8+ T-cells. We
hypothesize that this is a physiological process in immune regulation, and that it occurs …

T-cells produce acidic niches in lymph nodes to suppress their own effector functions

H Wu, V Estrella, M Beatty, D Abrahams… - Nature …, 2020 - econpapers.repec.org
The acidic pH of tumors profoundly inhibits effector functions of activated CD8+ T-cells. We
hypothesize that this is a physiological process in immune regulation, and that it occurs …

T-cells produce acidic niches in lymph nodes to suppress their own effector functions

H Wu, V Estrella, M Beatty, D Abrahams… - Nature …, 2020 - ui.adsabs.harvard.edu
The acidic pH of tumors profoundly inhibits effector functions of activated CD8+ T-cells. We
hypothesize that this is a physiological process in immune regulation, and that it occurs …

[PDF][PDF] T-cells produce acidic niches in lymph nodes to suppress their own effector functions

H Wu, V Estrella, M Beatty, D Abrahams, A El-Kenawi - researchgate.net
Results Paracortical zones are acidic niches inside the lymph node. The pHe of inguinal
LNs in C57BL/6 (B6) mice was probed using pH-Low Insertion Peptide (pHLIP) a short …