Mathematical modeling and analysis of microwave-assisted freeze-drying in biopharmaceutical applications

J Park, JH Cho, RD Braatz - Computers & Chemical Engineering, 2021 - Elsevier
Freeze drying is an essential unit operation for the storage of biopharmaceuticals, with its
main weakness being the very long primary drying times required to sublimate all of the ice …

[PDF][PDF] Mathematical modeling and analysis of microwave-assisted freeze-drying in biopharmaceutical applications

J Park, JH Cho, RD Braatz - Computers and Chemical Engineering, 2021 - mit.edu
abstract Freeze drying is an essential unit operation for the storage of biopharmaceuticals,
with its main weakness being the very long primary drying times required to sublimate all of …

Mathematical modeling and analysis of microwave-assisted freeze-drying in biopharmaceutical applications

J Park, JH Cho, RD Braatz - Comput. Chem. Eng., 2021 - openreview.net
Highlights• Freeze-drying using concurrent microwave irradiation and heat conduction is
explored.• A mechanistic model predicts a factor of five reduction in the primary drying time.• …

[PDF][PDF] Mathematical modeling and analysis of microwave-assisted freeze-drying in biopharmaceutical applications

J Park, JH Cho, RD Braatz - Computers and Chemical Engineering, 2021 - mit.edu
abstract Freeze drying is an essential unit operation for the storage of biopharmaceuticals,
with its main weakness being the very long primary drying times required to sublimate all of …