Molecular dynamics simulation reveals structural and thermodynamic features of kinase activation by cancer mutations within the epidermal growth factor receptor

S Wan, PV Coveney - Journal of computational chemistry, 2011 - Wiley Online Library
The epidermal growth factor receptor (EGFR) is a major target for drugs in treating lung
carcinoma as it promotes cell growth and tumor progression. Structural studies have …

Molecular dynamics simulation reveals structural and thermodynamic features of kinase activation by cancer mutations within the epidermal growth factor receptor.

S Wan, PV Coveney - Journal of Computational Chemistry, 2011 - europepmc.org
The epidermal growth factor receptor (EGFR) is a major target for drugs in treating lung
carcinoma as it promotes cell growth and tumor progression. Structural studies have …

Molecular dynamics simulation reveals structural and thermodynamic features of kinase activation by cancer mutations within the epidermal growth factor receptor

S Wan, PV Coveney - Journal of computational chemistry, 2011 - pubmed.ncbi.nlm.nih.gov
The epidermal growth factor receptor (EGFR) is a major target for drugs in treating lung
carcinoma as it promotes cell growth and tumor progression. Structural studies have …

Molecular dynamics simulation reveals structural and thermodynamic features of kinase activation by cancer mutations within the epidermal growth factor receptor

S Wan, PV Coveney - Journal of Computational Chemistry, 2011 - infona.pl
The epidermal growth factor receptor (EGFR) is a major target for drugs in treating lung
carcinoma as it promotes cell growth and tumor progression. Structural studies have …