Clarithromycin, midazolam, and digoxin: application of PBPK modeling to gain new insights into drug–drug interactions and co-medication regimens

D Moj, N Hanke, H Britz, S Frechen, T Kanacher… - The AAPS journal, 2017 - Springer
Clarithromycin is a substrate and mechanism-based inhibitor of cytochrome P450 (CYP)
3A4 as well as a substrate and competitive inhibitor of P-glycoprotein (P-gp) and organic …

[PDF][PDF] Clarithromycin, Midazolam, and Digoxin: Application of PBPK Modeling to Gain New Insights into Drug–Drug Interactions and Co-medication Regimens

D Moj, N Hanke, H Britz, S Frechen, T Kanacher… - klinikum.uni-heidelberg.de
Clarithromycin is a substrate and mechanism-based inhibitor of cytochrome P450 (CYP)
3A4 as well as a substrate and competitive inhibitor of P-glycoprotein (P-gp) and organic …

Clarithromycin, Midazolam, and Digoxin: Application of PBPK Modeling to Gain New Insights into Drug–Drug Interactions and Co-medication Regimens

D Moj, N Hanke, H Britz, S Frechen, T Kanacher… - The AAPS Journal, 2016 - infona.pl
Clarithromycin is a substrate and mechanism-based inhibitor of cytochrome P450 (CYP)
3A4 as well as a substrate and competitive inhibitor of P-glycoprotein (P-gp) and organic …

Clarithromycin, Midazolam, and Digoxin: Application of PBPK Modeling to Gain New Insights into Drug-Drug Interactions and Co-medication Regimens.

D Moj, N Hanke, H Britz, S Frechen, T Kanacher… - The AAPS …, 2016 - europepmc.org
Clarithromycin is a substrate and mechanism-based inhibitor of cytochrome P450 (CYP)
3A4 as well as a substrate and competitive inhibitor of P-glycoprotein (P-gp) and organic …

Clarithromycin, Midazolam, and Digoxin: Application of PBPK Modeling to Gain New Insights into Drug-Drug Interactions and Co-medication Regimens

D Moj, N Hanke, H Britz, S Frechen… - The AAPS …, 2017 - pubmed.ncbi.nlm.nih.gov
Clarithromycin is a substrate and mechanism-based inhibitor of cytochrome P450 (CYP)
3A4 as well as a substrate and competitive inhibitor of P-glycoprotein (P-gp) and organic …

[引用][C] Clarithromycin, Midazolam, and Digoxin: Application of PBPK Modeling to Gain New Insights into Drug–Drug Interactions and Co-medication Regimens

D Moj, N Hanke, H Britz, S Frechen, T Kanacher… - The AAPS Journal, 2016 - cir.nii.ac.jp
Clarithromycin, Midazolam, and Digoxin: Application of PBPK Modeling to Gain New Insights
into Drug–Drug Interactions and Co-medication Regimens | CiNii Research CiNii 国立情報学 …