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Combining the 'bottom up'and 'top down'approaches in pharmacokinetic modelling: fitting PBPK models to observed clinical data

N Tsamandouras… - British journal of …, 2015 - Wiley Online Library
Pharmacokinetic models range from being entirely exploratory and empirical, to semi‐
mechanistic and ultimately complex physiologically based pharmacokinetic (PBPK) models …
被引用次数：271 相关文章

Combining the'bottom up'and'top down'approaches in pharmacokinetic modelling: fitting PBPK models to observed clinical data.

N Tsamandouras, A Rostami-Hodjegan… - British Journal of …, 2015 - europepmc.org
Pharmacokinetic models range from being entirely exploratory and empirical, to semi-
mechanistic and ultimately complex physiologically based pharmacokinetic (PBPK) models …
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[HTML][HTML] Combining the 'bottom up'and 'top down'approaches in pharmacokinetic modelling: fitting PBPK models to observed clinical data

N Tsamandouras, A Rostami-Hodjegan… - British Journal of …, 2015 - ncbi.nlm.nih.gov
Pharmacokinetic models range from being entirely exploratory and empirical, to semi-
mechanistic and ultimately complex physiologically based pharmacokinetic (PBPK) models …

[引用][C] Combining the" bottom-up" and" top-down" approaches in pharmacokinetic modelling: Fitting PBPK models to observed clinical data

N Tsamandouras… - British Journal of …, 2015 - research.manchester.ac.uk
Combining the "bottom-up" and "top-down" approaches in pharmacokinetic modelling: Fitting
PBPK models to observed clinical data — Research Explorer The University of Manchester …

[引用][C] Combining the 'bottom up'and 'top down'approaches in pharmacokinetic modelling: fitting PBPK models to observed clinical data

N Tsamandouras, A Rostami-Hodjegan… - British Journal of Clinical …, 2014 - cir.nii.ac.jp
Combining the ‘bottom up’ and ‘top down’ approaches in pharmacokinetic modelling: fitting
PBPK models to observed clinical data | CiNii Research CiNii 国立情報学研究所 学術情報 …

Combining the'bottom up'and'top down'approaches in pharmacokinetic modelling: fitting PBPK models to observed clinical data

N Tsamandouras, A Rostami-Hodjegan… - British Journal of Clinical …, 2015 - hero.epa.gov
Pharmacokinetic models range from being entirely exploratory and empirical, to semi-
mechanistic and ultimately complex physiologically based pharmacokinetic (PBPK) models …

Combining the'bottom up'and'top down'approaches in pharmacokinetic modelling: fitting PBPK models to observed clinical data

N Tsamandouras… - British journal of …, 2015 - pubmed.ncbi.nlm.nih.gov
Pharmacokinetic models range from being entirely exploratory and empirical, to semi-
mechanistic and ultimately complex physiologically based pharmacokinetic (PBPK) models …

Combining the 'bottom up'and 'top down'approaches in pharmacokinetic modelling: fitting PBPK models to observed clinical data

N Tsamandouras, A Rostami‐Hodjegan… - British Journal of Clinical …, 2014 - infona.pl
Pharmacokinetic models range from being entirely exploratory and empirical, to semi‐
mechanistic and ultimately complex physiologically based pharmacokinetic (PBPK) models …

Combining the'bottom up'and'top down'approaches in pharmacokinetic modelling: fitting PBPK models to observed clinical data.

N Tsamandouras… - British Journal of …, 2015 - search.ebscohost.com
Pharmacokinetic models range from being entirely exploratory and empirical, to semi-
mechanistic and ultimately complex physiologically based pharmacokinetic (PBPK) models …

Combining the'bottom up'and'top down'approaches in pharmacokinetic modelling: fitting PBPK models to observed clinical data.

N Tsamandouras, A Rostami-Hodjegan… - British Journal of …, 2015 - europepmc.org
Pharmacokinetic models range from being entirely exploratory and empirical, to semi-
mechanistic and ultimately complex physiologically based pharmacokinetic (PBPK) models …