Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments

X Sheng, Y Guan, Z Ma, J Wu, H Liu, C Qiu, S Vitale… - Nature …, 2021 - nature.com
The functional interpretation of genome-wide association studies (GWAS) is challenging due
to the cell-type-dependent influences of genetic variants. Here, we generated …
被引用次数：102 相关文章
[HTML] nih.gov

[HTML][HTML] Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments

X Sheng, Y Guan, Z Ma, J Wu, H Liu, C Qiu… - Nature …, 2021 - ncbi.nlm.nih.gov
The functional interpretation of GWAS remains challenging due to the cell-type dependent
influences of genetic variants. Here, we generated comprehensive maps of expression …

Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments

X Sheng, Z Ma, J Wu, H Liu, C Qiu, Z Miao, MJ Seasock… - bioRxiv, 2020 - biorxiv.org
The functional interpretation of GWAS remains challenging due to cell-type dependent
influences of genetic variants. Here, we generated comprehensive maps of expression …

Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments

X Sheng, Y Guan, Z Ma, J Wu, H Liu, C Qiu, S Vitale… - paper.sciencenet.cn
The functional interpretation of genome-wide association studies (GWAS) is challenging due
to the cell-type-dependent influences of genetic variants. Here, we generated …

Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments.

X Sheng, Y Guan, Z Ma, J Wu, H Liu, C Qiu, S Vitale… - 2021 - cabidigitallibrary.org
The functional interpretation of genome-wide association studies (GWAS) is challenging due
to the cell-type-dependent influences of genetic variants. Here, we generated …
[PDF] researchgate.net

[PDF][PDF] Mapping the genetic architecture of human traits to cell types in the kidney identifies 1 mechanisms of disease and potential treatments 2

MJ Seasock, M Palmer, MK Shin, KL Duffin, SS Pullen - researchgate.net
Here, we generated comprehensive maps of expression quantitative trait loci (eQTL) for 659
5 microdissected human kidney samples and identified cell-type eQTLs by mapping …

Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments.

X Sheng, Y Guan, Z Ma, J Wu, H Liu, C Qiu… - Nature …, 2021 - europepmc.org
The functional interpretation of GWAS remains challenging due to the cell-type dependent
influences of genetic variants. Here, we generated comprehensive maps of expression …
[PDF] archive.org

[PDF][PDF] Mapping the genetic architecture of human traits to cell types in the kidney identifies 1 mechanisms of disease and potential treatments 2

MJ Seasock, M Palmer, MK Shin, KL Duffin, SS Pullen - scholar.archive.org
Here, we generated comprehensive maps of expression quantitative trait loci (eQTL) for 659
5 microdissected human kidney samples and identified cell-type eQTLs by mapping …

Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments

X Sheng, Y Guan, Z Ma, J Wu, H Liu, C Qiu… - Nature …, 2021 - pubmed.ncbi.nlm.nih.gov
The functional interpretation of genome-wide association studies (GWAS) is challenging due
to the cell-type-dependent influences of genetic variants. Here, we generated …

[引用][C] Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments

X Sheng, Y Guan, Z Ma, J Wu, H Liu, C Qiu, S Vitale… - Nature Genetics, 2021 - cir.nii.ac.jp
Mapping the genetic architecture of human traits to cell types in the kidney identifies
mechanisms of disease and potential treatments | CiNii Research CiNii 国立情報学研究所 …