[HTML][HTML] Ribociclib leverages phosphodiesterase 4 inhibition in the treatment of neutrophilic inflammation and acute respiratory distress syndrome

PJ Chen, SH Chen, YL Chen, YH Wang, CY Lin… - Journal of Advanced …, 2024 - Elsevier
Introduction Overwhelming neutrophil activation and oxidative stress significantly contribute
to acute respiratory distress syndrome (ARDS) pathogenesis. However, the potential of …

Ribociclib leverages phosphodiesterase 4 inhibition in the treatment of neutrophilic inflammation and acute respiratory distress syndrome

PJ Chen, SH Chen, YL Chen, YH Wang… - Journal of advanced … - pubmed.ncbi.nlm.nih.gov
Introduction Overwhelming neutrophil activation and oxidative stress significantly contribute
to acute respiratory distress syndrome (ARDS) pathogenesis. However, the potential of …

Ribociclib leverages phosphodiesterase 4 inhibition in the treatment of neutrophilic inflammation and acute respiratory distress syndrome

PJ Chen, SH Chen, YL Chen, YH Wang… - Journal of Advanced …, 2024 - pure.lib.cgu.edu.tw
Introduction: Overwhelming neutrophil activation and oxidative stress significantly contribute
to acute respiratory distress syndrome (ARDS) pathogenesis. However, the potential of …

Ribociclib leverages phosphodiesterase 4 inhibition in the treatment of neutrophilic inflammation and acute respiratory distress syndrome.

PJ Chen, SH Chen, YL Chen, YH Wang… - Journal of Advanced …, 2024 - europepmc.org
Methods Primary human neutrophils were used to determine the therapeutic effects of
ribociclib on respiratory bursts, chemotactic responses, and inflammatory signaling. In vitro …

Ribociclib leverages phosphodiesterase 4 inhibition in the treatment of neutrophilic inflammation and acute respiratory distress syndrome

PJ Chen, SH Chen, YL Chen, YH Wang… - Journal of Advanced …, 2024 - pure.lib.cgu.edu.tw
摘要Introduction: Overwhelming neutrophil activation and oxidative stress significantly
contribute to acute respiratory distress syndrome (ARDS) pathogenesis. However, the …