More than bad luck: cancer and aging are linked to replication-driven changes to the epigenome

CJ Minteer, K Thrush, J Gonzalez, P Niimi… - Science …, 2023 - science.org
Aging is a leading risk factor for cancer. While it is proposed that age-related accumulation
of somatic mutations drives this relationship, it is likely not the full story. We show that aging …

More than bad luck: Cancer and aging are linked to replication-driven changes to the epigenome

CJ Minteer, K Thrush, J Gonzalez, P Niimi… - Science …, 2023 - pubmed.ncbi.nlm.nih.gov
Aging is a leading risk factor for cancer. While it is proposed that age-related accumulation
of somatic mutations drives this relationship, it is likely not the full story. We show that aging …

[HTML][HTML] More than bad luck: Cancer and aging are linked to replication-driven changes to the epigenome

CJ Minteer, K Thrush, J Gonzalez, P Niimi… - Science …, 2023 - ncbi.nlm.nih.gov
Aging is a leading risk factor for cancer. While it is proposed that age-related accumulation
of somatic mutations drives this relationship, it is likely not the full story. We show that aging …

[引用][C] More than bad luck: Cancer and aging are linked to replication-driven changes to the epigenome

CJ Minteer, K Thrush, J Gonzalez, P Niimi, M Rozenblit… - 2023 - europepmc.org
Aging is a leading carcinogen, with cancer risk increasing more than 4000% between the
ages of 25 and 65 (1). This staggering increase is not the entire cancer narrative (2), but it is …

More than bad luck: Cancer and aging are linked to replication-driven changes to the epigenome

CJ Minteer, K Thrush, J Gonzalez, P Niimi… - Science …, 2023 - ui.adsabs.harvard.edu
Aging is a leading risk factor for cancer. While it is proposed that age-related accumulation
of somatic mutations drives this relationship, it is likely not the full story. We show that aging …

More than bad luck: Cancer and aging are linked to replication-driven changes to the epigenome

CJ Minteer, K Thrush, J Gonzalez, P Niimi… - Science …, 2023 - experts.umn.edu
Aging is a leading risk factor for cancer. While it is proposed that age-related accumulation
of somatic mutations drives this relationship, it is likely not the full story. We show that aging …