… Alzheimer’s disease (AD) lacks protein biomarkers reflective of its diverse underlying … Here,
we used integrative proteomics to identify cerebrospinal fluid (CSF) biomarkers representing …

… , the optimal fluid source of biomarkers for diseases of the central nervous system. Proteomic
… been employed in several studies to identify new CSF biomarkers of disease. (5, 6) One of …

… and cognitive impairment might serve as AD fluid biomarkers. CSF-level elevation was
confirmed … omics studies, including proteomics, and their integration. Machine learning solutions …

… an unbiased integrative proteomic approach to identify novel AD fluid biomarkers reflective
of … To achieve this goal, we analyzed a total of four proteomic datasets, including two derived …

… We sought to identify biomarkers from biochemical, metabolic and proteomic screens that …
An integrative multi-variate approach was applied to the analysis of cerebrospinal fluid …

… The integration of proteomics and fluid and cell based technologies will ultimately lead to a
description of the molecular setup of normal and abnormal cellular and liquid systems within …

… fluids in the context of prospective biomarker discovery, and the marked 1000–1500-fold
dilution of body fluid … [51] reported methods for the differential integrative analysis of plasma. …

… the pool of available biomarkers in precision medicine and personalized nutrition for many
years. The integrated proteomic profiling of ten body fluids provided an overall cognition and …

… This review discusses the use of proximal fluids, including tissue interstitial fluid, for discovery
of novel protein-based disease biomarkers by proteomics and the strategies utilized for …

… of establishing valid biomarkers. In this review, we summarize the technical proteomic
platforms that are available along the different stages in the biomarker discovery pipeline, …