Integrated proteomics and network analysis identifies protein hubs and network alterations in Alzheimer's disease

Q Zhang, C Ma, M Gearing, PG Wang, LS Chin… - Acta neuropathologica …, 2018 - Springer
… of disease-associated proteome changes in human frontal cortex of sporadic AD patients
using an integrated approach that combines mass spectrometry-based quantitative proteomics, …

[HTML][HTML] Integrated proteomics and metabolomics analysis reveals hubs protein and network alterations in myasthenia gravis

T Tong, J Zhang, L Jia, P Liang, N Wang - Aging (Albany NY), 2022 - ncbi.nlm.nih.gov
… , our integrated proteomics and metabolomics analysis supply a systems-level view of proteome
… -associated protein network alterations involved. The identified co-expressed modules …

Applying mass spectrometry-based proteomics to genetics, genomics and network biology

M Gstaiger, R Aebersold - Nature Reviews Genetics, 2009 - nature.com
… in mutants at the scale of the proteome. We finally discuss examples that integrate proteomics
data with genomic and phenomic information to build network-centred models, which …

Integrated network analysis of transcriptomic and proteomic data in psoriasis

E Piruzian, S Bruskin, A Ishkin, R Abdeev… - BMC systems …, 2010 - Springer
… We developed network-based methodology for integrative analysis of high throughput data
sets of different types. Investigation of proteomics and transcriptomics data sets on psoriasis …

Signaling pathway network alterations in human ovarian cancers identified with quantitative mitochondrial proteomics

N Li, X Zhan - Epma Journal, 2019 - Springer
… -based molecular network studies in OCs from multiparameter systematic opinion and
emphasize the importance of OC multiomics such as integrating proteomics and transcriptomics in …

Pathway and network analysis in proteomics

X Wu, M Al Hasan, JY Chen - Journal of theoretical biology, 2014 - Elsevier
… In this work, researchers integrated network topological information and functional
information together, resulting in enhanced characterization of complex ovarian cancer drug …

Integrated analysis of global proteome, phosphoproteome and glycoproteome enables complementary interpretation of disease-related protein networks

JM Park, JH Park, DG Mun, J Bae, JH Jung, S Back… - Scientific reports, 2015 - nature.com
… -dimensional proteomic approach, including the SEPG and the integrated analyses …
alterations of disease-related networks in terms of CC1-4 of cellular networks and also key network

Integrated Proteomics and Protein Co-expression Network Analysis Identifies Novel Epileptogenic Mechanism in Mesial Temporal Lobe Epilepsy

A Srivastava, P Rajput, M Tripathi, PS Chandra… - Molecular …, 2024 - Springer
… with hub proteins that are altered in MTLE patients. Our study is the first to employ an
integrated approach of proteomics and protein co-expression network analysis to study patients …

Morphine regulated synaptic networks revealed by integrated proteomics and network analysis

SD Stockton, I Gomes, T Liu, C Moraje… - … & Cellular Proteomics, 2015 - ASBMB
… In this study we used subcellular fractionation and quantitative proteomics combined with
computational approaches to investigate the morphine-induced protein profile changes at the …

Integrative proteomics and phosphoproteomics in pulmonary arterial hypertension

W Xu, SAA Comhair, R Chen, B Hu, Y Hou, Y Zhou… - Scientific Reports, 2019 - nature.com
… To build a comprehensive human interactome network, we integrated data from a total of
18 differential bioinformatics databases with multiple experimental evidences. Specifically, we …