The immune system of the central nervous system (CNS) consists primarily of innate
immune cells. These are highly specialized macrophages found either in the parenchyma …

Microglia are parenchymal macrophages of the CNS; as professional phagocytes they are
important for maintenance of the brain's physiology. These cells are generated through …

Microglia are macrophages of the central nervous system (CNS) that continuously scrutinize
their environment for damage. They colonize the cephalic mesenchyme during …

Microglia are highly specialized tissue macrophages of the brain with dedicated functions in
neuronal development, homeostasis and recovery from pathology Despite their unique …

As immune sentinels of the central nervous system (CNS), microglia not only respond
rapidly to pathological conditions but also contribute to homeostasis in the healthy brain. In …

Proper development and function of the mammalian central nervous system (CNS) depend
critically on the activity of parenchymal sentinels referred to as microglia. Although microglia …

Microglia—resident myeloid-lineage cells in the brain and the spinal cord parenchyma—
function in the maintenance of normal tissue homeostasis. Microglia also act as sentinels of …

As resident macrophages of the central nervous system (CNS), microglia are associated
with diverse functions essential to the developing and adult brain during homeostasis and …

Multiple Sclerosis (MS) is a neurodegenerative disease characterized by multiple focal
lesions, ongoing demyelination and, for most people, a lack of remyelination. MS lesions are …

Macrophages are major cell types of the immune system, and they comprise both tissue‐
resident populations and circulating monocyte‐derived subsets. Here, we discuss microglia …