Anti‐inflammatory and antiviral roles of hydrogen sulfide: Rationale for considering H2S donors in COVID‐19 therapy

V Citi, A Martelli, V Brancaleone, S Brogi… - British journal of …, 2020 - Wiley Online Library
The COVID‐19 pandemic caused by SARS‐Cov‐2 demands rapid, safe and effective
therapeutic options. In the last decades, the endogenous gasotransmitter hydrogen sulfide …

[HTML][HTML] H2S Donors and Their Use in Medicinal Chemistry

E Magli, E Perissutti, V Santagada, G Caliendo… - Biomolecules, 2021 - mdpi.com
Hydrogen sulfide (H2S) is a ubiquitous gaseous signaling molecule that has an important
role in many physiological and pathological processes in mammalian tissues, with the same …

H2S as a potential defense against COVID-19?

G Yang - American Journal of Physiology-Cell Physiology, 2020 - journals.physiology.org
The outbreak of COVID-19 pneumonia caused by a new coronavirus (severe acute
respiratory syndrome coronavirus 2, SARS-CoV-2) is posing a global health emergency and …

[HTML][HTML] Possible application of H2S-producing compounds in therapy of coronavirus (COVID-19) infection and pneumonia

MB Evgen'ev, A Frenkel - Cell Stress and Chaperones, 2020 - Springer
Objectives Based on the above data and considerations, we suggest the application of a
harmless H2S donor (sodium thiosulfate) to treat patients at any stage of the COVID-19 virus …

N-acetylcysteine and hydrogen sulfide in coronavirus disease 2019

AR Bourgonje, AK Offringa, LE van Eijk… - Antioxidants & redox …, 2021 - liebertpub.com
Significance: Hydrogen sulfide (H2S) is one of the three main gasotransmitters that are
endogenously produced in humans and are protective against oxidative stress. Recent …

Progress and perspective on hydrogen sulfide donors and their biomedical applications

ZL Song, L Zhao, T Ma, A Osama… - Medicinal Research …, 2022 - Wiley Online Library
Following the discovery of nitric oxide (NO) and carbon monoxide (CO), hydrogen sulfide
(H2S) has been identified as the third gasotransmitter in humans. Increasing evidence have …

Hydrogen sulfide in inflammation: friend or foe?

A Hegde, M Bhatia - … & Allergy-Drug Targets (Formerly Current …, 2011 - ingentaconnect.com
Hydrogen sulfide (H2S), the gaseous mediator produced by various cells in our body, was
recently discovered to play a major role in human physiology despite its toxic nature known …

[HTML][HTML] The role of hydrogen sulfide in respiratory diseases

S Khattak, QQ Zhang, M Sarfraz, P Muhammad… - Biomolecules, 2021 - mdpi.com
Respiratory diseases are leading causes of death and disability around the globe, with a
diverse range of health problems. Treatment of respiratory diseases and infections has been …

Hydrogen sulfide: a novel player in airway development, pathophysiology of respiratory diseases, and antiviral defenses

N Bazhanov, M Ansar, T Ivanciuc… - American journal of …, 2017 - atsjournals.org
Hydrogen sulfide (H2S) is a biologically relevant signaling molecule in mammals. Along with
the volatile substances nitric oxide (NO) and carbon monoxide (CO), H2S is defined as a …

[HTML][HTML] Use of thiols in the treatment of COVID-19: current evidence

M Cazzola, P Rogliani, SS Salvi, J Ora, MG Matera - Lung, 2021 - Springer
There is a possible role for oxidative stress, a state characterized by an altered balance
between the production of free radicals or reactive oxygen species (ROS) and antioxidant …