Immunometabolic Signature during Respiratory Viral Infection: A Potential Target for Host-Directed Therapies

L Menezes dos Reis, MR Berçot, BG Castelucci… - Viruses, 2023 - mdpi.com
RNA viruses are known to induce a wide variety of respiratory tract illnesses, from simple
colds to the latest coronavirus pandemic, causing effects on public health and the economy …

[HTML][HTML] Immunometabolism pathways as the basis for innovative anti-viral strategies (INITIATE): A Marie Sklodowska-Curie innovative training network

B van den Hoogen, A Santoni, G Sciumé, A Bowie… - Virus research, 2020 - Elsevier
The past century has witnessed major advances in the control of many infectious diseases,
yet outbreaks and epidemics caused by (re-) emerging RNA viruses continue to pose a …

Hijacking the supplies: metabolism as a novel facet of virus-host interaction

KA Mayer, J Stöckl, GJ Zlabinger… - Frontiers in …, 2019 - frontiersin.org
Viral replication is a process that involves an extremely high turnover of cellular molecules.
Since viruses depend on the host cell to obtain the macromolecules needed for their proper …

Role of metabolism during viral infections, and crosstalk with the innate immune system

JJG Plaza, N Hulak, G Kausova… - Intractable & rare …, 2016 - jstage.jst.go.jp
Viruses have been for long polemic biological particles which stand in the twilight of being
living entities or not. As their genome is reduced, they rely on the metabolic machinery of …

Cellular metabolism hijacked by viruses for immunoevasion: potential antiviral targets

J Li, Y Wang, H Deng, S Li, HJ Qiu - Frontiers in Immunology, 2023 - frontiersin.org
Cellular metabolism plays a central role in the regulation of both innate and adaptive
immunity. Immune cells utilize metabolic pathways to modulate the cellular differentiation or …

Metabolic reprogramming and immune regulation in viral diseases

GV Ganesh, RK Mohanram - Reviews in medical virology, 2022 - Wiley Online Library
The recent outbreak and transmission of the severe acute respiratory syndrome coronavirus
2 (SARS‐CoV‐2) worldwide and the ensuing coronavirus disease 2019 (COVID‐19) …

Interplay between cellular metabolism and cytokine responses during viral infection

S Zhang, J Carriere, X Lin, N Xie, P Feng - Viruses, 2018 - mdpi.com
Metabolism and immune responses are two fundamental biological processes that serve to
protect hosts from viral infection. As obligate intracellular pathogens, viruses have evolved …

The interaction between viruses and the host immune system in persistent infection from a metabolic perspective

W Xiong, Y Feng, Y Qiu, Y Yuan… - Frontiers in Cellular and …, 2023 - frontiersin.org
In recent years, our understanding of viral infections and their intricate dance with the host
immune system has evolved significantly. The traditional view of host-pathogen interactions …

[HTML][HTML] Impact of viruses on host metabolism

M Arslan, X Yang - Hosts and Viruses, 2019 - researcherslinks.com
Viruses are obligate intracellular pathogens and rely on host machinery to successfully
cause infections. In order to succumb hosts, viruses have evolved strategies to manipulate …

The Influence of Metabolism on Immune Response: A Journey to Understand Immunometabolism in the Context of Viral Infection

D El Safadi, A Paulo-Ramos, M Hoareau, M Roche… - Viruses, 2023 - mdpi.com
In recent years, the emergence of the concept of immunometabolism has shed light on the
pivotal role that cellular metabolism plays in both the activation of immune cells and the …