Rapid developments in Regenerative Medicine and Tissue Engineering has witnessed an
increasing drive toward clinical translation of breakthrough technologies. However, the …

Opinion Barré-Sinoussi & Montagutelli but also on the fact that human diseases often affect
other animal species. It is particularly the case for most infectious diseases but also for very …

The field of regenerative medicine is moving toward translation to clinical practice. However,
there are still knowledge gaps and safety concerns regarding stem cell-based therapies …

Noncommunicable diseases, including cardiovascular disease, diabetes, chronic respiratory
disease, and cancer, are the leading cause of death in the world. The cost, both monetary …

For ages, regeneration has intrigued countless biologists, clinicians, and biomedical
engineers. In recent years, significant progress made in identification and characterization of …

In the tissue engineering (TE) paradigm, engineering and life sciences tools are combined
to develop bioartificial substitutes for organs and tissues, which can in turn be applied in …

The field of regenerative medicine is approaching translation to clinical practice, and
significant safety concerns and knowledge gaps have become clear as clinical practitioners …

The animal model deals with the species other than the human, as it can imitate the disease
progression, its' diagnosis as well as a treatment similar to human. Discovery of a drug …

[Frontiers in Bioscience 12, 4864-4880, September 1, 2007] 4864 The importance of large
animal models in transplantation Jean-P Page 1 [Frontiers in Bioscience 12, 4864-4880 …

Simple Summary We review the value of large animal models for improving the translation of
biomedical research for human application, focusing primarily on sheep. Abstract An …