Endothelial dysfunction is principally characterized by impaired endothelium–dependent
transduction mechanisms related to vascular relaxation, as an outcome of decreased …

The endothelium constitutes the inner lining of the vessels and is a cornerstone of vascular
homeostasis. Besides their classical barrier function, the endothelial cells are notably …

The endothelium is considered to be the gatekeeper of the vessel wall, maintaining and
regulating vascular integrity. In patients with chronic kidney disease, protective endothelial …

The vascular endothelium is a dynamic, functionally complex organ, modulating multiple
biological processes, including vascular tone and permeability, inflammatory responses …

Renal dysfunction and cardiovascular disorders affect each other adversely and worsen
existing pathophysiological conditions. These disorders are extremely diverse in terms of …

Accumulating evidence indicates that the pathological changes of the endothelium may
contribute to the development of cardiovascular complications in chronic kidney disease …

In chronic kidney disease (CKD) patients, several risk factors contribute to the development
of endothelial dysfunction (ED), which can be described as an alteration in the cell structure …

Endothelium is the largest organ in the body strategically located between the wall of blood
vessels and the blood stream. The human body contains approximately 1013 endothelial …

Endothelial dysfunction has been implicated as a key factor in the development of a wide
range of cardiovascular diseases, but its definition and mechanisms vary greatly between …

Endothelial dysfunction has been posited to play an important role in the pathogenesis of
diabetic nephropathy (DN). Due to the heterogeneity of endothelial cells (ECs), it is difficult …