Tissue-based proteomic profiling in patients with hyperplasia and endometrial cancer

K Akkour, IO Alanazi, AA Alfadda, H Alhalal, A Masood… - Cells, 2022 - mdpi.com
Uterine cancers are among the most prevalent gynecological malignancies, and
endometrial cancer (EC) is the most common in this group. This study used tissue-based …

Plasma-based proteomic profiling identifies the distinct regulation of proteins in hyperplasia and endometrial cancer

K Akkour, IO Alanazi, AA Alfadda, A Masood, H Alhalal… - BMC cancer, 2024 - Springer
Background Among gynaecological malignancies, endometrial cancer (EC) is the most
prevalent type of uterine cancer affecting women. This study explored the proteomic profiles …

Comprehensive serum proteomic analysis in early endometrial cancer

DS Uyar, YW Huang, MA Chesnik, NB Doan… - Journal of …, 2021 - Elsevier
Objective Endometrial cancer is the most common gynecologic cancer and yet much is still
unknown about this disease. Our goal was to identify unique biomarkers of disease by …

Proteomics-based approach identified differentially expressed proteins with potential roles in endometrial carcinoma

Z Li, W Min, C Huang, S Bai, M Tang… - International Journal of …, 2010 - ijgc.bmj.com
Instruction: We used proteomic approaches to identify altered expressed proteins in
endometrial carcinoma, with the aim of discovering potential biomarkers or therapeutic …

A Multi-omics approach revealed common dysregulated pathways in type one and type two endometrial cancers

V Capaci, L Monasta, M Aloisio, E Sommella… - International Journal of …, 2023 - mdpi.com
Endometrial cancer (EC) is the most frequent gynecologic cancer in postmenopausal
women. Pathogenetic mechanisms that are related to the onset and progression of the …

Proteomic analysis in endometrial cancer and endometrial hyperplasia tissues by 2D-DIGE technique

Y Ceylan, G Akpınar, E Doger, M Kasap… - Journal of Gynecology …, 2020 - Elsevier
Objective To compare the protein expression of complex atypical endometrial hyperplasia,
endometrial carcinoma and healthy endometrial tissues, and by this way, to identify proteins …

Proteomic analysis of stage I endometrial cancer tissue: identification of proteins associated with oxidative processes and inflammation

GL Maxwell, BL Hood, R Day, U Chandran… - Gynecologic …, 2011 - Elsevier
Objective The present study aimed to identify differentially expressed proteins employing a
high resolution mass spectrometry (MS)-based proteomic analysis of endometrial cancer …

Altered protein expression in serum from endometrial hyperplasia and carcinoma patients

Y Wang, R Cao, H Jin, Y Huang, X Zhang… - Journal of Hematology & …, 2011 - Springer
Background Endometrial carcinoma is one of the most common gynecological malignancies
in women. The diagnosis of the disease at early or premalignant stages is crucial for the …

Serum Proteomic Profiles of Patients with High and Low Risk of Endometrial Cancer Recurrence

D Pietkiewicz, MP Zaborowski, K Jaz… - International Journal of …, 2023 - mdpi.com
Endometrial cancer is the most common gynecological cancer worldwide. Classifying
endometrial cancer into low-or high-risk groups based on the following features is …

Identification of novel molecular targets for endometrial cancer using a drill-down LC-MS/MS approach with iTRAQ

SN Voisin, O Krakovska, A Matta, LV DeSouza… - PloS one, 2011 - journals.plos.org
Background The number of patients with endometrial carcinoma (EmCa) with advanced
stage or high histological grade is increasing and prognosis has not improved for over the …