The helicase protein of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-
2) is both a good potential drug target and very flexible. The flexibility, and therefore its …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the pandemic that broke out in 2020 and continues to be the cause of massive global …

The RNA helicase (non-structural protein 13, NSP13) of SARS-CoV-2 is essential for viral
replication, and it is highly conserved among the coronaviridae family, thus a prominent drug …

The raging COVID-19 pandemic caused by SARS-CoV-2 has infected tens of millions of
people and killed several hundred thousand patients worldwide. Currently, there are no …

To date, effective therapeutic treatments that confer strong attenuation against coronaviruses
(CoVs) remain elusive. Among potential drug targets, the helicase of CoVs is attractive due …

We have assembled a computational pipeline based on virtual screening, docking
techniques, and nonequilibrium molecular dynamics simulations, with the goal of identifying …

Abstract The SARS-CoV-2 helicase Nsp13 is a promising target for developing anti-COVID
drugs. In the present study, we have identified potential natural product inhibitors of SARS …

The rise in the incidence of COVID-19 as a result of SARS-CoV-2 infection has threatened
public health globally. Till now, there have been no proper prophylactics available to fight …

There is currently a lack of effective drugs to treat people infected with SARS-CoV-2, the
cause of the global COVID-19 pandemic. The SARS-CoV-2 Non-structural protein 13 …

The landscape of viral strains and lineages of SARS-CoV-2 keeps changing and is currently
dominated by Delta and Omicron variants. Members of the latest Omicron variants, including …