V Goede - Frailty in Older Adults with Cancer, 2022 - Springer
The majority of hematological cancers are age-associated diseases. Therefore, many patients with hematological malignancies are older and may present with frailty, ie the loss …
AM Mahmoud, F Biello, PM Maggiora, R Bruna… - BMC geriatrics, 2021 - Springer
Background Age is considered as one of the most important risk-factor for many types of solid and hematological cancers, as their incidence increases with age in parallel to the ever …
ME Hamaker, MC Prins, R Stauder - Leukemia research, 2014 - Elsevier
Background Geriatric assessment is increasingly used to assess the health status of older cancer patients. We set out to assemble all available evidence on the relevance of a …
G Gugliotta, F Castagnetti, M Apolinari, S Pirondi… - Drugs, 2014 - Springer
Chronic myeloid leukemia (CML) is a disease of the hematopoietic stem cell characterized by a median age at diagnosis of 60–65 years according to most epidemiologic registries …
M Breccia, M Tiribelli, G Alimena - Critical reviews in oncology/hematology, 2012 - Elsevier
The impact of age as a poor prognostic factor in chronic myeloid leukemia (CML) has been well described. In the interferon era, elderly patients diagnosed as having chronic phase …
Clinicians often report that currently available methods to assess older patients, including standard clinical consultations, do not elicit the information necessary to make an …
D Russo, M Malagola, C Skert, C Filì… - Current Cancer Drug …, 2013 - ingentaconnect.com
The prevalence of chronic myeloid leukemia (CML) is expected to double in the next 15 years. The introduction of imatinib significantly changed the prognosis of CML, challenging …
A Iurlo, A Nobili, R Latagliata, C Bucelli, F Castagnetti… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Background About 40% of all patients with chronic myeloid leukemia are currently old or very old. They are effectively treated with imatinib, even though underrepresented in clinical …
Simple Summary As life expectancy is increasing, the older population is rapidly growing. However, older patients with cancer are still underrepresented in clinical trials, making …