Longevity and disease-free survival are influenced by a combination of genetics and
lifestyle. Biological age (BioAge), a measure of aging based on composite biomarkers, may …

Genome‐wide and hypothesis‐based approaches to the study of ageing and longevity have
been dominated by genetic investigations. To identify essential mechanisms of a complex …

Given the rising rate of survival into advanced old age in the United States, achieving
longevity and healthy aging is becoming increasingly important. Besides maintaining …

The choice of a phenotype is critical for the study of a complex genetically regulated
process, such as aging. To date, most of the twin and family studies have focused on broad …

Background and Objective: The influence of genes on human lifespan is mediated by
biological processes that characterize body's functioning. The age trajectories of these …

Population aging is a global trend and requires better evidence-based guidance. This thesis
studied population aging from a molecular epidemiological angle. The overall work is …

This commentary calls attention to the value of combining genetic and epidemiologic
methods in studies to understand the determinants of two crucial aspects of aging: ages at …

Increasing proportions of elderly individuals in developed countries combined with
substantial increases in related medical expenditures make the improvement of the health of …

Background An individual's rate of aging directly influences his/her susceptibility to morbidity
and mortality. Thus, quantifying aging and disentangling how various factors coalesce to …

Background We tested the association of biologic age (BA) measures constructed from
different types of biomarkers with mortality and disease in a community-based sample …