COVID-19 transmission, current treatment, and future therapeutic strategies

VS Salian, JA Wright, PT Vedell, S Nair… - Molecular …, 2021 - ACS Publications
At the stroke of the New Year 2020, COVID-19, a zoonotic disease that would turn into a
global pandemic, was identified in the Chinese city of Wuhan. Although unique in its …

The hallmarks of COVID-19 disease

D Tang, P Comish, R Kang - PLoS pathogens, 2020 - journals.plos.org
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel coronavirus that
has caused a worldwide pandemic of the human respiratory illness COVID-19, resulting in a …

Recent progress and challenges in drug development against COVID-19 coronavirus (SARS-CoV-2)-an update on the status

TM Abd El-Aziz, JD Stockand - Infection, Genetics and Evolution, 2020 - Elsevier
Coronaviruses are a large group of viruses known to cause illnesses that vary between the
common cold and more severe diseases to include severe acute respiratory syndrome …

Epidemiology, pathogenesis, clinical presentations, diagnosis and treatment of COVID-19: a review of current evidence

S Rahman, MTV Montero, K Rowe… - Expert review of …, 2021 - Taylor & Francis
Introduction The COVID-19 pandemic has created a public health crisis, infected millions of
people, and caused a significant number of deaths. SARS-CoV-2 transmits from person to …

The human coronavirus disease COVID-19: its origin, characteristics, and insights into potential drugs and its mechanisms

L Alanagreh, F Alzoughool, M Atoum - Pathogens, 2020 - mdpi.com
The emerging coronavirus disease (COVID-19) swept across the world, affecting more than
200 countries and territories. Genomic analysis suggests that the COVID-19 virus originated …

Potential therapeutic targets and promising drugs for combating SARS‐CoV‐2

H Zhou, Y Fang, T Xu, WJ Ni, AZ Shen… - British Journal of …, 2020 - Wiley Online Library
As of April 9, 2020, a novel coronavirus (SARS‐CoV‐2) had caused 89,931 deaths and
1,503,900 confirmed cases worldwide, which indicates an increasingly severe and …

COVID-19: characteristics and therapeutics

R Chilamakuri, S Agarwal - Cells, 2021 - mdpi.com
Novel coronavirus (COVID-19 or 2019-nCoV or SARS-CoV-2), which suddenly emerged in
December 2019 is still haunting the entire human race and has affected not only the …

SARS-CoV-2: An update on potential antivirals in light of SARS-CoV antiviral drug discoveries

HA Elshabrawy - Vaccines, 2020 - mdpi.com
Coronaviruses (CoVs) are a group of RNA viruses that are associated with different
diseases in animals, birds, and humans. Human CoVs (HCoVs) have long been known to …

The recent outbreaks of human coronaviruses: A medicinal chemistry perspective

T Pillaiyar, LL Wendt, M Manickam… - Medicinal research …, 2021 - Wiley Online Library
Coronaviruses (CoVs) infect both humans and animals. In humans, CoVs can cause
respiratory, kidney, heart, brain, and intestinal infections that can range from mild to lethal …

COVID-19 outbreak: pathogenesis, current therapies, and potentials for future management

MF Hossain, S Hasana, AA Mamun… - Frontiers in …, 2020 - frontiersin.org
At the end of 2019, a novel coronavirus (CoV) was found at the seafood market of Hubei
province in Wuhan, China, and this virus was officially named coronavirus diseases 2019 …