High-throughput glycomic methods

I Trbojević-Akmačić… - Chemical …, 2022 - ACS Publications
Glycomics aims to identify the structure and function of the glycome, the complete set of
oligosaccharides (glycans), produced in a given cell or organism, as well as to identify …

Deciphering the glycocode: the complexity and analytical challenge of glycomics

KT Pilobello, LK Mahal - Current opinion in chemical biology, 2007 - Elsevier
Carbohydrates coat most types of cell in nature and are intimately involved in various
biological events, including cell differentiation, homing to specific tissues, cell adhesion, cell …

Developments and perspectives in high-throughput protein glycomics: enabling the analysis of thousands of samples

N de Haan, M Pučić-Baković, M Novokmet… - …, 2022 - academic.oup.com
Glycans expand the structural complexity of proteins by several orders of magnitude,
resulting in a tremendous analytical challenge when including them in biomedical research …

Recent advances in glycoinformatic platforms for glycomics and glycoproteomics

JL Abrahams, G Taherzadeh, G Jarvas… - Current opinion in …, 2020 - Elsevier
Highlights•Recent advancements in glycoinformatics tools to support analysis of glycan and
glycopeptide data sets are summarised.•Review summarises the growth of machine …

Clinical application of quantitative glycomics

W Peng, J Zhao, X Dong, A Banazadeh… - Expert review of …, 2018 - Taylor & Francis
Introduction: Aberrant glycosylation has been associated with many diseases. Decades of
research activities have reported many reliable glycan biomarkers of different diseases …

Comprehensive approach to structural and functional glycomics based on chemoselective glycoblotting and sequential tag conversion

J Furukawa, Y Shinohara, H Kuramoto… - Analytical …, 2008 - ACS Publications
Changes in protein glycosylation profoundly affect protein function. To understand these
effects of altered protein glycosylation, we urgently need high-throughput technologies to …

N‐glycome signatures in human plasma: associations with physiology and major diseases

V Dotz, M Wuhrer - FEBS letters, 2019 - Wiley Online Library
N‐glycome analysis in total plasma or serum yields information about the levels and
glycosylation patterns of major plasma glycoproteins, including immunoglobulins, acute …

Lectin microarrays for glycomic analysis

G Gupta, A Surolia… - Omics: a journal of …, 2010 - liebertpub.com
Glycomics is the study of comprehensive structural elucidation and characterization of all
glycoforms found in nature and their dynamic spatiotemporal changes that are associated …

[HTML][HTML] High-throughput analysis and automation for glycomics studies

A Shubhakar, KR Reiding, RA Gardner, DIR Spencer… - Chromatographia, 2015 - Springer
This review covers advances in analytical technologies for high-throughput (HTP) glycomics.
Our focus is on structural studies of glycoprotein glycosylation to support biopharmaceutical …

Glycomics and disease markers

HJ An, SR Kronewitter, MLA de Leoz… - Current opinion in …, 2009 - Elsevier
Glycomics is the comprehensive study of all glycans expressed in biological systems. The
biosynthesis of glycan relies on a number of highly competitive processes involving glycosyl …