[HTML][HTML] Association of Molnupiravir and Nirmatrelvir-Ritonavir with reduced mortality and sepsis in hospitalized omicron patients: A territory-wide study

AK Wai, TT Lee, SC Chan, CY Chan, ET Yip, LY Luk… - Scientific Reports, 2023 - nature.com
This study evaluates the association between antivirals (Molnupiravir and Nirmatrelvir-
Ritonavir) and all-cause and respiratory mortality and organ dysfunction among high-risk …

[HTML][HTML] Effectiveness of molnupiravir vs nirmatrelvir-ritonavir in non-hospitalised and hospitalised patients with COVID-19: a target trial emulation study

EYF Wan, VKC Yan, ZCT Wong, CSL Chui… - …, 2023 - thelancet.com
Background Molnupiravir and nirmatrelvir-ritonavir have emerged as promising options for
COVID-19 treatment, but direct comparisons of their effectiveness have been limited. This …

Non-randomized evaluation of hospitalization after a prescription for nirmatrelvir/ritonavir versus molnupiravir in high-risk COVID-19 outpatients

K Cowman, A Miller, Y Guo, MH Chang… - Journal of …, 2023 - academic.oup.com
Objectives To assess and compare subsequent hospital admissions within 30 days for
patients after receiving a prescription for either oral nirmatrelvir/ritonavir or oral molnupiravir …

Real-world effectiveness of molnupiravir and nirmatrelvir/ritonavir among COVID-19 inpatients during Hong Kong's Omicron BA. 2 wave: an observational study

CKH Wong, ICH Au, KTK Lau, EHY Lau, BJ Cowling… - medRxiv, 2022 - medrxiv.org
Background Real-world evidence on the effectiveness of oral antivirals in mild-to-moderate
COVID-19 patients is urgently needed. This retrospective cohort study aims to evaluate the …

Impact of the use of oral antiviral agents on the risk of hospitalization in community coronavirus disease 2019 patients (COVID-19)

TCF Yip, GCY Lui, MSM Lai, VWS Wong… - Clinical infectious …, 2023 - academic.oup.com
Background We examined the effectiveness of molnupiravir and nirmatrelvir/ritonavir in
reducing hospitalization and deaths in a real-world cohort of nonhospitalized patients with …

Nirmatrelvir or molnupiravir use and severe outcomes from omicron infections

DY Lin, F Abi Fadel, S Huang, AT Milinovich… - JAMA Network …, 2023 - jamanetwork.com
Importance Ritonavir-boosted nirmatrelvir and molnupiravir are currently used in the US and
in other countries to treat nonhospitalized patients who have mild-to-moderate COVID-19 …

Real-world Effectiveness of Molnupiravir and Nirmatrelvir/Ritonavir as Treatments for COVID-19 in Patients at High Risk

D Paraskevis, M Gkova, K Mellou… - The Journal of …, 2023 - academic.oup.com
Background Using a retrospective cohort study design, we aimed to evaluate the
effectiveness of molnupiravir and nirmatrelvir/ritonavir in patients with SARS-CoV-2 who …

Real-world effectiveness of molnupiravir and nirmatrelvir plus ritonavir against mortality, hospitalisation, and in-hospital outcomes among community-dwelling …

CKH Wong, ICH Au, KTK Lau, EHY Lau, BJ Cowling… - The Lancet, 2022 - thelancet.com
Background Little is known about the real-world effectiveness of oral antivirals against the
SARS-CoV-2 omicron (B. 1.1. 529) variant. We aimed to assess the clinical effectiveness of …

[HTML][HTML] Association of Molnupiravir and Nirmatrelvir-Ritonavir with preventable mortality, hospital admissions and related avoidable healthcare system cost among …

AKC Wai, CY Chan, AWL Cheung, K Wang… - The Lancet Regional …, 2023 - thelancet.com
Background Real-world data is currently limited on the association between oral antiviral
therapy and healthcare system burden in patients with mild-to-moderate COVID-19. This …

Effectiveness of molnupiravir and nirmatrelvir–ritonavir in hospitalized patients with COVID-19: a target trial emulation study

EYF Wan, VKC Yan, AHY Mok, B Wang… - Annals of internal …, 2023 - acpjournals.org
Background: Whether hospitalized patients benefit from COVID-19 oral antivirals is
uncertain. Objective: To examine the real-world effectiveness of molnupiravir and …