DirectRMDB: a database of post-transcriptional RNA modifications unveiled from direct RNA sequencing technology
With advanced technologies to map RNA modifications, our understanding of them has
been revolutionized, and they are seen to be far more widespread and important than …
been revolutionized, and they are seen to be far more widespread and important than …
[HTML][HTML] Analysis of RNA modifications by second-and third-generation deep sequencing: 2020 update
Y Motorin, V Marchand - Genes, 2021 - mdpi.com
The precise mapping and quantification of the numerous RNA modifications that are present
in tRNAs, rRNAs, ncRNAs/miRNAs, and mRNAs remain a major challenge and a top priority …
in tRNAs, rRNAs, ncRNAs/miRNAs, and mRNAs remain a major challenge and a top priority …
RMBase: a resource for decoding the landscape of RNA modifications from high-throughput sequencing data
Although more than 100 different types of RNA modifications have been characterized
across all living organisms, surprisingly little is known about the modified positions and their …
across all living organisms, surprisingly little is known about the modified positions and their …
Exploring the epitranscriptome by native RNA sequencing
Chemical RNA modifications, collectively referred to as the “epitranscriptome,” are essential
players in fine-tuning gene expression. Our ability to analyze RNA modifications has …
players in fine-tuning gene expression. Our ability to analyze RNA modifications has …
Next-generation sequencing technologies for detection of modified nucleotides in RNAs
S Schwartz, Y Motorin - RNA biology, 2017 - Taylor & Francis
Our ability to map and quantify RNA modifications at a genome-wide scale have
revolutionized our understanding of the pervasiveness and dynamic regulation of diverse …
revolutionized our understanding of the pervasiveness and dynamic regulation of diverse …
[HTML][HTML] Detection technologies for RNA modifications
Y Zhang, L Lu, X Li - Experimental & Molecular Medicine, 2022 - nature.com
To date, more than 170 chemical modifications have been characterized in RNA, providing a
new layer of gene expression regulation termed the 'epitranscriptome'. RNA modification …
new layer of gene expression regulation termed the 'epitranscriptome'. RNA modification …
Understanding RNA modifications: the promises and technological bottlenecks of the 'epitranscriptome'
The discovery of mechanisms that alter genetic information via RNA editing or introducing
covalent RNA modifications points towards a complexity in gene expression that challenges …
covalent RNA modifications points towards a complexity in gene expression that challenges …
[HTML][HTML] Methods for RNA modification mapping using deep sequencing: established and new emerging technologies
New analytics of post-transcriptional RNA modifications have paved the way for a
tremendous upswing of the biological and biomedical research in this field. This especially …
tremendous upswing of the biological and biomedical research in this field. This especially …
[HTML][HTML] RNA modifications detection by comparative Nanopore direct RNA sequencing
RNA molecules undergo a vast array of chemical post-transcriptional modifications (PTMs)
that can affect their structure and interaction properties. In recent years, a growing number of …
that can affect their structure and interaction properties. In recent years, a growing number of …
DRUMMER—rapid detection of RNA modifications through comparative nanopore sequencing
Motivation The chemical modification of ribonucleotides regulates the structure, stability and
interactions of RNAs. Profiling of these modifications using short-read (Illumina) sequencing …
interactions of RNAs. Profiling of these modifications using short-read (Illumina) sequencing …