Malaria caused by Plasmodium is still a serious public health problem. Genomic editing is
essential to understand parasite biology, elucidate mechanical pathways, uncover gene …

CRISPR/Cas9 approaches are revolutionizing our ability to perform functional genomics
across a wide range of organisms, including the Plasmodium parasites that cause malaria …

The∼ 30 Mb genomes of the Plasmodium parasites that cause malaria each encode∼
5000 genes, but the functions of the majority remain unknown. This is due to a paucity of …

Studies of molecular mechanisms and related gene functions have long been restricted by
limited genome editing technologies in malaria parasites. Recently, a simple and effective …

Malaria as vector-borne disease remains important health concern with over 200 million
cases globally. Novel antimalarial medicines and more effective vaccines must be …

Malaria remains a major global health issue, affecting millions and killing hundreds of
thousands of people annually. Efforts to break the transmission cycle of the causal …

The CRISPR/Cas9 system is a powerful genetic engineering technology for Plasmodium
falciparum. We here report further improvement of the CRISPR/Cas9 system by combining …

CRISPR/Cas9 technology has been developing rapidly in the field of parasitology, allowing
for the dissection of molecular processes with unprecedented efficiency. Optimization and …

The ability to interrogate gene function in Plasmodium parasites has been greatly enhanced
by the advent of CRISPR/Cas9 systems. The breadth of genome manipulations ranges from …

Background Plasmodium falciparum is the deadliest malaria parasite. Currently, there are
seldom commercial antibodies against P. falciparum proteins, which greatly limits the study …