Importance Schizophrenia is a clinically heterogeneous disorder. It is currently unclear how
variability in symptom dimensions and cognitive ability is associated with genetic liability for …

Background Cognitive impairment is a clinically important feature of schizophrenia.
Polygenic risk score (PRS) methods have demonstrated genetic overlap between …

Studying the phenotypic manifestations of increased genetic liability for schizophrenia can
increase our understanding of this disorder. Specifically, information from alleles identified in …

Cognitive impairment is a core feature of schizophrenia but there is limited understanding of
the genetic relationship between cognition in the general population and schizophrenia. We …

Psychotic disorders including schizophrenia are commonly accompanied by cognitive
deficits. Recent studies have reported negative genetic correlations between schizophrenia …

Schizophrenia is a multifactorial disease associated with widespread cognitive impairment.
Although cognitive deficits are one of the factors most strongly associated with functional …

Cognitive impairments are considered core features in schizophrenia and other psychotic
disorders. Cognitive impairments are, to a lesser degree, also documented in healthy first …

Content TheDSM-IVconcept of schizophrenia offers diagnostic reliability but etiologic and
pathologic heterogeneity, which probably contributes to the inconsistencies in genetic …

Background Psychotic disorders and schizotypal traits aggregate in the relatives of
probands with schizophrenia. It is currently unclear how variability in symptom dimensions in …

Objective: Genetic factors contribute to the development of schizophrenia where cognitive
dysfunction is a hallmark. The purpose of this article was to examine computerized …