Macrophage immunotherapy is an emerging treatment strategy that modulates the immune
system to promote wound healing. The functionality and regeneration of tissue depend on …

Endogenous regeneration aims to rebuild and reinstate tissue function through enlisting
natural self-repairing processes. Promoting endogenous regeneration by reducing tissue …

Macrophages have long been known for their phagocytic capabilities and immune defence;
however, their role in healing is being increasingly recognized in recent years due to their …

Macrophages are versatile and plastic effector cells of the immune system, and contribute to
diverse immune functions including pathogen or apoptotic cell removal, inflammatory …

Skin wound repair is a multistage process involving multiple cellular and molecular
interactions, which modulate the cell behaviors and dynamic remodeling of extracellular …

Tissue regeneration is an active multiplex process involving the dynamic inflammatory
microenvironment. Under a normal physiological framework, inflammation is necessary for …

An immune response involves the action of all types of macrophages, classically activated
subtype (M1) in the early inflammatory phase and regulatory and wound-healing subtypes …

The host response to biomaterials has been studied for decades. Largely, the interaction of
host immune cells, macrophages in particular, with implanted materials has been …

Musculoskeletal disorders are common in clinical practice. Repairing critical-sized defects in
musculoskeletal systems remains a challenge for researchers and surgeons, requiring the …

Recent research in the vaccine and immunotherapy fields has revealed that biomaterials
have the ability to activate immune pathways, even in the absence of other immune …