Infections are a major threat to human reproductive health, and infections in pregnancy can
cause prematurity or stillbirth, or can be vertically transmitted to the fetus leading to …

Congenital infections with pathogens such as Zika virus, Toxoplasma gondii, Listeria
monocytogenes, Treponema pallidium, parvovirus, HIV, varicella zoster virus, Rubella …

Infection by bacteria, viruses, and parasites may lead to fetal death, organ injury, or limited
sequelae depending on the pathogen. Here, we consider the role of infection during …

Pregnancy causes physiological and immunological adaptations that allow the mother and
fetus to communicate with precision in order to promote a healthy pregnancy. At the same …

Toxoplasma gondii is a ubiquitous, obligate intracellular parasite capable of crossing the
placenta to cause spontaneous abortion, preterm labor, or significant disease in the …

The immunologic paradigm of pregnancy led to the conceptualization of pregnancy as an
organ transplant that requires, for its success, suppression of the maternal immune system …

Viral infections during pregnancy are associated with adverse pregnancy outcomes,
including maternal and fetal mortality, pregnancy loss, premature labor, and congenital …

Placental infections are major causes of maternal and fetal disease. This review introduces
a new paradigm for placental infections based on current knowledge of placental defenses …

The placenta is a highly specialized organ that is formed during human gestation for
conferring protection and generating an optimal microenvironment to maintain the …

During pregnancy, the placenta forms the anatomical barrier between the mother and
developing fetus. Infectious agents can potentially breach the placental barrier resulting in …