Oral delivery of nanoparticle-based vaccines

N Marasini, M Skwarczynski, I Toth - Expert Review of Vaccines, 2014 - Taylor & Francis
Most infectious diseases are caused by pathogenic infiltrations from the mucosal tract.
Therefore, vaccines delivered to the mucosal tissues can mimic natural infections and …

Nano and microparticles as potential oral vaccine carriers and adjuvants against infectious diseases

SD Jazayeri, HX Lim, K Shameli, SK Yeap… - Frontiers in …, 2021 - frontiersin.org
Mucosal surfaces are the first site of infection for most infectious diseases and oral
vaccination can provide protection as the first line of defense. Unlike systemic …

Nanoparticles for mucosal vaccine delivery

A Thakur, C Foged - Nanoengineered biomaterials for advanced drug …, 2020 - Elsevier
Mucosal surfaces represent important routes of entry into the human body for the majority of
pathogens, and they constitute unique sites for targeted vaccine delivery. Nanoparticle …

Recent developments in oral delivery of vaccines using nanocarriers

A Zafar, R Arshad, A Ur. Rehman, N Ahmed, H Akhtar - Vaccines, 2023 - mdpi.com
As oral administration of vaccines is the preferred route due to its high patient compliance
and ability to stimulate both cellular and humoral immune responses, it is also associated …

Oral vaccines: directed safe passage to the front line of defense

Q Zhu, JA Berzofsky - Gut Microbes, 2013 - Taylor & Francis
Oral vaccines are safe and easy to administer and convenient for all ages. They have been
successfully developed to protect from many infectious diseases acquired through oral …

Mechanistic study of the adjuvant effect of biodegradable nanoparticles in mucosal vaccination

B Slütter, L Plapied, V Fievez, MA Sande… - Journal of Controlled …, 2009 - Elsevier
For oral vaccination, incorporation of antigens into nanoparticles has been shown to protect
the antigen from degradation, but may also increase its uptake through the intestinal …

Nanotechnology solutions for mucosal immunization

S Chadwick, C Kriegel, M Amiji - Advanced drug delivery reviews, 2010 - Elsevier
The current prevalence of infectious diseases in many developing regions of the world is a
serious burden, impacting both the general health as well as economic growth of these …

[HTML][HTML] Tailoring functional nanoparticles for oral vaccine delivery: recent advances and future perspectives

P Cao, ZP Xu, L Li - Composites Part B: Engineering, 2022 - Elsevier
The oral vaccine has attracted much interest due to easy administration, induction of local
and systemic immune responses, and pain relief. Nowadays, functional nanoparticles and …

Nanovaccines for oral delivery-formulation strategies and challenges

S Karandikar, A Mirani, V Waybhase… - Nanostructures for Oral …, 2017 - Elsevier
The specialized field of research in vaccination is experiencing potential advances. The
majority of the currently used vaccines are administered by parenteral route. This route …

Polymer nanotechnology based approaches in mucosal vaccine delivery: challenges and opportunities

R Sharma, U Agrawal, N Mody, SP Vyas - Biotechnology advances, 2015 - Elsevier
Mucosal sites serve as the main portal for the entry of pathogens and thus immunization
through mucosal routes can greatly improve the immunity. Researchers are continuously …