Mitochondria, independent double-membrane organelles, are intracellular power plants that
feed most eukaryotic cells with the ATP produced via the oxidative phosphorylation …

Cytochrome c oxidase subunit VIc (COX6c) is one of the most important subunits of the
terminal enzyme of the respiratory chain in mitochondria. Numerous studies have …

Cytochrome-c-oxidase (COX) subunit 4 (COX4) plays important roles in the function,
assembly and regulation of COX (mitochondrial respiratory complex 4), the terminal electron …

Simple Summary Targeting the metabolism of cancers is a promising strategy for treatment.
In the current study we examine the role of COX4, an enzyme of the mitochondria, in thyroid …

Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain,
plays a key role in regulating mitochondrial energy production and cell survival. COX …

COX7A1, a subunit of cytochrome c oxidase, holds an important position in the super-
assembly which integrates into multi-unit heteromeric complexes peripherally in the …

Mitochondrial Dysfunction has been implicated in multiple human diseases, including
cancer. Among all cancer, lung cancer is the most common type of cancer worldwide with …

Mitochondria provide the main portion of cellular energy in form of ATP produced by the
F1Fo ATP synthase, which uses the electrochemical gradient, generated by the …

COX5B, a peripheral subunit of the cytochrome c oxidase complex, has previously been
reported to maintain the stability of this complex. However, its functions and mechanisms …

Genetic defects in the nuclear encoded subunits and assembly factors of cytochrome c
oxidase (mitochondrial complex IV) are very rare and are associated with a wide variety of …