The biology of peroxisome proliferator activated receptors (PPARs) in physiological and
pathophysiological processes has been primarily studied in peripherial organs and tissues …

Peroxisome proliferator activated receptors (PPARs) are well studied for their role of
peripheral metabolism, but they also may be involved in the pathogenesis of various …

The finding that activation of peroxisome proliferator-activated receptor-γ (PPARγ)
suppresses inflammation in peripheral macrophages and in models of human autoimmune …

Alzheimer's disease (AD) is characterized by the extracellular deposition of β-amyloid fibrils
within the brain and the subsequent association and phenotypic activation of microglial cells …

The role of inflammatory processes in the brains of Alzheimer's Disease (AD) patients has
recently attracted considerable interest. Indeed, the only demonstrated effective therapy for …

Over 25 years have passed since peroxisome proliferators‐activated receptors (PPARs),
were first described. Like other members of the nuclear receptors superfamily, PPARs have …

Agonists of the peroxisome proliferator activated receptor gamma (PPARγ) have been
shown to reduce inflammatory responses in several animal models of neurological diseases …

Peroxisome proliferator‐activated receptor‐γ (PPAR‐γ) plays a critical role in glucose and
lipid metabolism. More recently, PPAR‐γ ligands have been reported to inhibit the …

Alzheimer's disease is a complex neurodegenerative disorder, with aging, genetic and
environmental factors contributing to its development and progression. The complexity of …

Abstract peroxisome proliferator-activated receptors (PPARs) are nuclear receptors acting
as lipid sensors. Besides its metabolic activity in peripheral organs, the PPAR beta/delta …