A semi-automated alumina-based extraction method for the determination of l-dopa and
dopamine in plasma using liquid chromatography/mass spectrometry was validated. The …

A method based on LC–MS–MS is described for the determination of methyldopa in human
plasma using dopa-phenyl-D3 as the internal standard. The method has a chromatographic …

Background: Two methods have been developed and validated for the determination of free
and total dopamine in human plasma. They are based on solid-phase extraction of the …

A sensitive, simple and rapid LC–MS–MS method has been developed and validated for the
simultaneous determination of l-dopa and l-dopa n-pentyl ester hydrochloride in rat plasma …

A high performance liquid chromatography (HPLC) method was developed to detected
simultaneously l-dihydroxyphenylalanine (l-DOPA), dopamine (DA), dihydroxyphenylacetic …

A sensitive, simple and rapid HPLC–MS/MS method has been developed and validated for
the simultaneous determination of l-dopa and its prodrug (S)-4-(2-acetamido-3-ethoxy-3 …

Abstract l-3-(3, 4-Dihydroxyphenyl) alanine (DOPA) and its 3-O-methyl metabolite (OMD)
were measured in plasma and cerebrospinal fluid by a new assay which combines N, O …

A simple and ultra rapid high performance liquid chromatographic (HPLC) method coupled
with alumina extraction and fluorescence detection was described for determination of …

The treatment of Parkinson's disease is still based on substitution therapy with L_3, 4-
dihydroxyphenylalanine(L-DOPA) in spite of the side-effects (dyskinesia, on-off phenomena …

We describe a new method for the simultaneous assay of 3, 4-dihydroxyphenylalanine (L-
dopa) and dopamine in serum. Both compounds have been determined quantitatively at …