A radiobiological model of radiotherapy response and its correlation with prognostic imaging variables

M Crispin-Ortuzar, J Jeong… - Physics in Medicine & …, 2017 - iopscience.iop.org
Radiobiological models of tumour control probability (TCP) can be personalized using
imaging data. We propose an extension to a voxel-level radiobiological TCP model in order …

Visual analysis of tumor control models for prediction of radiotherapy response

RG Raidou, O Casares‐Magaz… - Computer Graphics …, 2016 - Wiley Online Library
In radiotherapy, tumors are irradiated with a high dose, while surrounding healthy tissues
are spared. To quantify the probability that a tumor is effectively treated with a given dose …

[HTML][HTML] Uncertainty evaluation of image-based tumour control probability models in radiotherapy of prostate cancer using a visual analytic tool

O Casares-Magaz, RG Raidou, J Rørvik… - Physics and Imaging in …, 2018 - Elsevier
Functional imaging techniques provide radiobiological information that can be included into
tumour control probability (TCP) models to enable individualized outcome predictions in …

A TCP model incorporating setup uncertainty and tumor cell density variation in microscopic extension to guide treatment planning

JY Jin, FM Kong, D Liu, L Ren, H Li, H Zhong… - Medical …, 2011 - Wiley Online Library
Purpose: Tumor control probability (TCP) models have been proposed to evaluate and
guide treatment planning. However, they are usually based on the dose volume histograms …

Increasing the power of tumour control and normal tissue complication probability modelling in radiotherapy: recent trends and current issues

F Tommasino, A Nahum, L Cella - Translational Cancer Research, 2017 - tcr.amegroups.org
The release of a homogeneous high dose to the tumour region has been one of the
cornerstones of radiotherapy (RT) treatment since its early days. According to the organ type …

Implementation of a model for estimating tumor control probability for an inhomogeneously irradiated tumor

A Niemierko, M Goitein - Radiotherapy and Oncology, 1993 - Elsevier
This paper presents the details of a practical implementation of a model for the prediction of
the tumor control probability (TCP) when a tumor is irradiated non-uniformly. The …

[引用][C] Radiobiological modelling in radiation oncology

B Warkentin - 2008 - Wiley Online Library
Radiobiological Modelling in Radiation Oncology Dale Roger and Jones Bleddyn The
British Institute of Radiology, London, UK, 2007. publications@ bir. org. uk,£ 60.0. ISBN …

Impact of dose and sensitivity heterogeneity on TCP

K Wiklund, I Toma-Dasu, BK Lind - … and Mathematical Methods …, 2014 - Wiley Online Library
This present paper presents an analytical description and numerical simulations of the
influence of macroscopic intercell dose variations and intercell sensitivity variations on the …

Monte Carlo role in radiobiological modelling of radiotherapy outcomes

I El Naqa, P Pater, J Seuntjens - Physics in Medicine & Biology, 2012 - iopscience.iop.org
Radiobiological models are essential components of modern radiotherapy. They are
increasingly applied to optimize and evaluate the quality of different treatment planning …

Computer simulation of tumour control probabilities after irradiation for varying intrinsic radio-sensitivity using a single cell based model

C Harting, P Peschke, CP Karger - Acta Oncologica, 2010 - Taylor & Francis
Background. Currently, optimisation of the dose distribution and clinical acceptance are
almost entirely based on the physical dose distribution and tumour control probability …