The humoral immune response to BCG vaccination

R Tanner, B Villarreal-Ramos… - Frontiers in …, 2019 - frontiersin.org
Bacillus Calmette Guérin (BCG) is the only currently available vaccine against tuberculosis
(TB), but it confers incomplete and variable protection against pulmonary TB in humans and …

The influence of BCG on vaccine responses–a systematic review

P Zimmermann, N Curtis - Expert review of vaccines, 2018 - Taylor & Francis
ABSTRACT Introduction: Bacillus Calmette-Guérin (BCG) vaccine is one of the most widely
used vaccines worldwide. In addition to providing protection against tuberculosis, it has non …

Development and challenges in animal tuberculosis vaccination

A Balseiro, J Thomas, C Gortázar, MA Risalde - Pathogens, 2020 - mdpi.com
Vaccination with Bacillus Calmette–Guérin (BCG) constituted a major advance in the
prevention of human tuberculosis (TB) in the beginning of the past century. BCG has also a …

BCG vaccination strategies against tuberculosis: updates and perspectives

M Qu, X Zhou, H Li - Human Vaccines & Immunotherapeutics, 2021 - Taylor & Francis
ABSTRACT Bacillus Calmette-Guérin (BCG) is the only licensed vaccine against
tuberculosis (TB). However, BCG has variable efficacy and cannot completely prevent TB …

Next-generation vaccines based on Bacille Calmette–Guérin

NE Nieuwenhuizen, SHE Kaufmann - Frontiers in immunology, 2018 - frontiersin.org
Tuberculosis (TB), caused by the intracellular bacterium Mycobacterium tuberculosis (Mtb),
remains a major health threat. A live, attenuated mycobacterium known as Bacille Calmette …

Prospects in Mycobacterium bovis Bacille Calmette et Guérin (BCG) vaccine diversity and delivery: why does BCG fail to protect against tuberculosis?

JI Moliva, J Turner, JB Torrelles - Vaccine, 2015 - Elsevier
Mycobacterium tuberculosis (M. tb) infection leads to active tuberculosis (TB), a disease that
kills one human every 18 s. Current therapies available to combat TB include chemotherapy …

A review of the BCG vaccine and other approaches toward tuberculosis eradication

T Cho, C Khatchadourian, H Nguyen… - Human vaccines & …, 2021 - Taylor & Francis
Despite aggressive eradication efforts, Tuberculosis (TB) remains a global health burden,
one that disproportionally affects poorer, less developed nations. The only vaccine approved …

[HTML][HTML] The diverse applications of recombinant BCG-based vaccines to target infectious diseases other than tuberculosis: an overview

E Mouhoub, P Domenech, M Ndao… - Frontiers in …, 2021 - frontiersin.org
Live attenuated Bacillus Calmette-Guérin (BCG) is the world's most widely used vaccine
which is mainly administered for its protection against tuberculosis (TB), particularly in young …

A meta-analysis of the effect of Bacillus Calmette-Guérin vaccination against bovine tuberculosis: is perfect the enemy of good?

S Srinivasan, AJK Conlan, LA Easterling… - Frontiers in Veterinary …, 2021 - frontiersin.org
More than 50 million cattle are likely exposed to bovine tuberculosis (bTB) worldwide,
highlighting an urgent need for bTB control strategies in low-and middle-income countries …

The success and failure of BCG—implications for a novel tuberculosis vaccine

P Andersen, TM Doherty - Nature Reviews Microbiology, 2005 - nature.com
Over the past 50 years, the Mycobacterium bovis bacille Calmette–Guérin (BCG) vaccine
against tuberculosis (TB) has maintained its position as the world's most widely used …