Image-guided Raman spectroscopy navigation system to improve transperineal prostate cancer detection. Part 1: Raman spectroscopy fiber-optics system and in situ …

F Picot, R Shams, F Dallaire, G Sheehy… - Journal of …, 2022 - spiedigitallibrary.org
Significance: The diagnosis of prostate cancer (PCa) and focal treatment by brachytherapy
are limited by the lack of precise intraoperative information to target tumors during biopsy …

Image-guided Raman spectroscopy navigation system to improve transperineal prostate cancer detection. Part 2: in-vivo tumor-targeting using a classification model …

D Grajales, F Picot, R Shams, F Dallaire… - Journal of …, 2022 - spiedigitallibrary.org
Significance: The diagnosis and treatment of prostate cancer (PCa) are limited by a lack of
intraoperative information to accurately target tumors with needles for biopsy and …

Raman spectroscopy system for real‐time diagnosis of clinically significant prostate cancer tissue

SJ van Breugel, I Low, ML Christie… - Journal of …, 2023 - Wiley Online Library
Prostate cancer (PCa) is a significant healthcare problem worldwide. Current diagnosis and
treatment methods are limited by a lack of precise in vivo tissue analysis methods. Real‐time …

Integration of a Raman spectroscopy system to a robotic-assisted surgical system for real-time tissue characterization during radical prostatectomy procedures

M Pinto, KC Zorn, JP Tremblay… - Journal of …, 2019 - spiedigitallibrary.org
Surgical excision of the whole prostate through a radical prostatectomy procedure is part of
the standard of care for prostate cancer. Positive surgical margins (cancer cells having …

Mesoscopic characterization of prostate cancer using Raman spectroscopy: potential for diagnostics and therapeutics

K Aubertin, VQ Trinh, M Jermyn, P Baksic… - BJU …, 2018 - Wiley Online Library
Objective To test if Raman spectroscopy (RS) is an appropriate tool for the diagnosis and
possibly grading of prostate cancer (PC a). Patients and Methods Between 20 and 50 …

Combining high wavenumber and fingerprint Raman spectroscopy for the detection of prostate cancer during radical prostatectomy

K Aubertin, J Desroches, M Jermyn, VQ Trinh… - Biomedical optics …, 2018 - opg.optica.org
For prostate cancer (PCa) patients, radical prostatectomy (complete removal of the prostate)
is the only curative surgical option. To date, there is no clinical technique allowing for real …

Raman spectroscopy in prostate cancer: techniques, applications and advancements

F Gaba, WJ Tipping, M Salji, K Faulds, D Graham… - Cancers, 2022 - mdpi.com
Simple Summary Raman spectroscopic analysis is a promising and powerful optical
investigative tool to interrogate tissue and/or biofluids for in vitro and in vivo applications …

Dimensional reduction based on peak fitting of Raman micro spectroscopy data improves detection of prostate cancer in tissue specimens

A Plante, F Dallaire, AA Grosset… - Journal of …, 2021 - spiedigitallibrary.org
Significance: Prostate cancer is the most common cancer among men. An accurate
diagnosis of its severity at detection plays a major role in improving their survival. Recently …

Assessment of fiberoptic near-infrared Raman spectroscopy for diagnosis of bladder and prostate cancer

P Crow, A Molckovsky, N Stone, J Uff, B Wilson… - Urology, 2005 - Elsevier
OBJECTIVES: To determine whether a fiberoptic Raman system, suitable for in vivo use, is
able to differentiate between benign and malignant bladder and prostate pathologic findings …

Stimulated Raman histology, a novel method to allow for rapid pathologic examination of unprocessed, fresh prostate biopsies

MP Mannas, D Jones, FM Deng, D Hoskoppal… - The …, 2023 - Wiley Online Library
Introduction Delay between targeted prostate biopsy (PB) and pathologic diagnosis can lead
to a concern of inadequate sampling and repeated biopsy. Stimulated Raman histology …