A major depressive disorder is a serious mental illness characterized by a pervasive low
mood that negatively concerns personal life, work life, or education, affecting millions of …

Depression is the most prevalent mental disorder in the world associated with huge socio-
economic consequences. While depressive-related symptoms are well known, the …

Objectives The first drug repurposed for the treatment of depression was the tuberculostatic
iproniazid. At present, drugs belonging to new classes of antidepressants still have …

The microbiome residing in the human gut performs a wide range of biological functions.
Recently, it has been elucidated that a change in dietary habits is associated with alteration …

An emerging body of literature demonstrates differences in the gut microbiome (GMB) of
patients with major depressive disorder (MDD) compared to healthy controls (HC), as well …

Background There is a growing body of evidence suggesting that disturbance of the gut-
brain axis may be one of the potential causes of major depressive disorder (MDD). However …

Depression, a prevalent mood disorder, has emerged as a significant health concern in
society. While the exact cause of depression remains incompletely understood, there is …

Depression is considered a multifaceted and intricate mental disorder of growing concern
due to its significant impact on global health issues. The human gut microbiota, also known …

This systematic review evaluated the animal and human evidence for
pharmacomicrobiomics (PMx) interactions of antidepressant medications. Studies of gut …

Major depressive disorder is one of the most disabling mental disorders worldwide.
Increasing preclinical and clinical studies have highlighted that compositional and functional …