DNA microarray chip assay in new use: early diagnostic value in cutaneous mycobacterial infection

Q Yu, Y Wang, Z Gao, H Yang, S Liu, J Tan… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction The clinical practicability of DNA microarray chip in detecting the presence of
mycobacterial species/isolates directly in the skin tissues has not been evaluated, nor the …

Skin tests for the detection of Mycobacterial infections: achievements, current perspectives, and implications for other diseases

MS Duthie, SG Reed - Applied Microbiology and Biotechnology, 2021 - Springer
Immunological and molecular advances have modernized diagnostic testing for many
diseases. Although interferon gamma-release and polymerase chain reaction assays have …

High-throughput identification of clinically important bacterial pathogens using DNA microarray

SM Yoo, SY Lee, KH Chang, SY Yoo, NC Yoo… - Molecular and cellular …, 2009 - Elsevier
Rapid and accurate detection of pathogenic bacteria is important for the treatment of patients
with suitable antibiotics. Here we report the development of a diagnostic DNA microarray for …

Bug or no bug: challenges in diagnosing cutaneous mycobacterial infections

F Peters, M Batinica, G Plum… - JDDG: Journal der …, 2016 - Wiley Online Library
Cutaneous mycobacterioses are rare in Germany. Nevertheless, early diagnosis and
subsequent effective treatment requires awareness of these conditions. Moreover …

Application of real-time PCR to recognize atypical mycobacteria in archival skin biopsies: high prevalence of Mycobacterium haemophilum

LSB van Coppenraet, VT Smit… - Diagnostic Molecular …, 2007 - journals.lww.com
Atypical mycobacterial skin infections are difficult to diagnose owing to their aspecific
histopathologic presentations and to the presence of few bacteria. Therefore, these …

Simple PCR-based DNA microarray system to identify human pathogenic fungi in skin

T Sato, A Takayanagi, K Nagao… - Journal of clinical …, 2010 - Am Soc Microbiol
Fungal diseases in immunocompromised hosts pose significant threats to their prognoses.
An accurate diagnosis and identification of the fungal pathogens causing the infection are …

Cutaneous mycobacterial infections

C Franco-Paredes, LA Marcos… - Clinical microbiology …, 2018 - Am Soc Microbiol
Humans encounter mycobacterial species due to their ubiquity in different environmental
niches. In many individuals, pathogenic mycobacterial species may breach our first-line …

[PDF][PDF] Comparison between real-time polymerase chain reaction and DNA-microarray in detection and identification of Mycobacterium species

A Gaber, H Hamed, E Elsawy - Genet Mol Res, 2017 - academia.edu
Low-cost and low-density (LCD) DNA arrays offer an easy way to detect resistance as
minimal laboratory instrumentation is needed. Nucleic acid-based amplification tests allow …

Development of a DNA microarray for detection and identification of fungal pathogens involved in invasive mycoses

DM Leinberger, U Schumacher… - Journal of clinical …, 2005 - Am Soc Microbiol
Invasive fungal infections have emerged as a major cause of morbidity and mortality in
immunocompromised patients. Conventional identification of pathogenic fungi in clinical …

Visible DNA microarray system as an adjunctive molecular test in identification of pathogenic fungi directly from a blood culture bottle

LL Sturaro, T Gonoi, AF Busso-Lopes… - Journal of Clinical …, 2018 - Am Soc Microbiol
ABSTRACT A DNA microarray platform, based on the nucleotide sequences of the internal
transcribed spacer regions (ITS1 and ITS2) of the rRNA gene, was developed to identify 32 …