[HTML][HTML] A mesenchymal stem cell-derived nanovesicle-biopotentiated bovine serum albumin-bridged gelatin hydrogel for enhanced diabetic wound therapy

Y Wu, M Su, S Zhang, L Xiao, Y Xiao, M Zhang, Y Bei… - Materials & Design, 2023 - Elsevier
The application of gelatin hydrogels is hampered by their poor mechanical properties, which
are unfavorable for debridement and diabetic wound healing. Herein, bovine serum albumin …

Glycopeptide-based multifunctional nanofibrous hydrogel that facilitates the healing of diabetic wounds infected with methicillin-resistant Staphylococcus aureus

W Liu, S Liu, M Sun, F Guo, P Wang, L Jia, D Wang… - Acta Biomaterialia, 2024 - Elsevier
Diabetic wound management remains a significant challenge in clinical care due to bacterial
infections, excessive inflammation, presence of excessive reactive oxygen species (ROS) …

Bone marrow mesenchymal stem cells preconditioned with nitric-oxide-releasing chitosan/PVA hydrogel accelerate diabetic wound healing in rabbits

R Ahmed, A Afreen, M Tariq, AA Zahid… - Biomedical …, 2021 - iopscience.iop.org
Impaired diabetic wounds are one of the major pathophysiological complications caused by
persistent microbial infections, prolonged inflammation, and insufficient angiogenic …

Facile strategy for gelatin-based hydrogel with multifunctionalities to remodel wound microenvironment and accelerate healing of acute and diabetic wounds

C Wang, H Chen, W Wang, G Yan, S Zheng… - International Journal of …, 2024 - Elsevier
Chronic diabetic wounds represent the most common diabetes complication. Wound healing
depends on scavenging reactive oxygen species (ROS), neovascularization, and controlling …

Mesenchymal stem cell-laden anti-inflammatory hydrogel enhances diabetic wound healing

S Chen, J Shi, M Zhang, Y Chen, X Wang, L Zhang… - Scientific reports, 2015 - nature.com
The purpose of this study was to permit bone marrow mesenchymal stem cells (BMSCs) to
reach their full potential in the treatment of chronic wounds. A biocompatible multifunctional …

In situ photo-crosslinked adhesive hydrogel loaded with mesenchymal stem cell-derived extracellular vesicles promotes diabetic wound healing

Y Wang, P Song, L Wu, Z Su, X Gui, C Gao… - Journal of Materials …, 2023 - pubs.rsc.org
The delayed healing of diabetic wounds is directly affected by the disturbance of wound
microenvironment, resulting from persistent inflammation, insufficient angiogenesis, and …

Snail-inspired AFG/GelMA hydrogel accelerates diabetic wound healing via inflammatory cytokines suppression and macrophage polarization

Z Zhou, T Deng, M Tao, L Lin, L Sun, X Song, D Gao… - Biomaterials, 2023 - Elsevier
Diabetic foot ulcers (DFUs) are a severe and rapidly growing diabetic complication, but
treating DFUs remains a challenge for the existing therapies are expensive and highly non …

Adhesive, injectable, and ROS-responsive hybrid polyvinyl alcohol (PVA) hydrogel co-delivers metformin and fibroblast growth factor 21 (FGF21) for enhanced …

H Zhu, J Xu, M Zhao, H Luo, M Lin, Y Luo… - … in bioengineering and …, 2022 - frontiersin.org
As conventional treatments for diabetic wounds often fail to achieve rapid satisfactory
healing, the development of effective strategies to accelerate diabetic wound repair is highly …

[HTML][HTML] Harnessing a biopolymer hydrogel reinforced by copper/tannic acid nanosheets for treating bacteria-infected diabetic wounds

S You, Y Xiang, X Qi, R Mao, E Cai, Y Lan, H Lu… - Materials Today …, 2022 - Elsevier
Current diabetic wound treatments remain difficult in clinical due to bacterial infection and
excessive reactive oxygen species (ROS). An ideal wound dressing should have prominent …

Multifunctional extracellular matrix hydrogel with self-healing properties and promoting angiogenesis as an immunoregulation platform for diabetic wound healing

Z Sun, H Xiong, T Lou, W Liu, Y Xu, S Yu, H Wang… - Gels, 2023 - mdpi.com
Treating chronic wounds is a global challenge. In diabetes mellitus cases, long-time and
excess inflammatory responses at the injury site may delay the healing of intractable …